UNLABELLED The whole genome shotgun approach to genome sequencing results in a collection of contigs that must be ordered and oriented to facilitate efficient gap closure. We present a new tool OSLay that uses synteny between matching sequences in a target assembly and a reference assembly to layout the contigs (or scaffolds) in the target assembly. The underlying algorithm is based on maximum ...

This paper addresses a major issue in fixture layout design to determine and evaluate the acceptable fixture designs based on multiple quality criteria and to select an optimal fixture with appropriate trade-offs among multiple performance requirements. The performance objectives considered are related to the fundamental requirements of kinematic localization and total fixturing (formclosure). ...

This paper presents an overview of recent advances on modeling and layout optimization of devices and interconnects for high-performance VLSI circuit design under the deep submicron technology. First, we review a number of interconnect and driver/gate delay models, which are most useful to guide the layout optimization. Then, we summarize the available performance optimization techniques for VL...

This paper presents a performance metric for the document structure extraction algorithms by finding the correspondences between detected entities and ground truth. We describe a method for determining an algorithm’s optimal tuning parameters. We evaluate a group of document layout analysis algorithms on 1600 images from the UW-III Document Image Database, and the quantitative performance measu...

Modelica is an object-oriented language for modeling of large and heterogeneous physical systems. Typical applications include mechatronic models in automotive and aerospace applications involving mechanical, electrical and hydraulic subsystems as well as control systems. Modeling of an ideal diode and Coulomb friction is discussed to illustrate the unique hybrid features of Modelica. The langu...

Abstract–Planetary gearbox is widely used in many fields due to its robustness and high power-weight ratio, but implementation of fault diagnosis on it is challenging. This paper proposes a new fault diagnosis method for planetary gearbox based on empirical mode decomposition (EMD) and adaptive multi-scale morphological gradient filter (AMMGF). The proposed method has two dominant strengths: it...

Good data layouts improve cache and TLB performance of object-oriented software, but unfortunately, selecting an optimal data layout a priori is NP-hard. This paper introduces layout auditing, a technique that selects the best among a set of layouts online (while the program is running). Layout auditing randomly applies different layouts over time and observes their performance. As it becomes c...