نتایج جستجو برای: oral delivery

تعداد نتایج: 450344  

Journal: :Journal of Oral Medicine and Oral Surgery 2019

Journal: :South African Dental Journal 2017

Journal: :Precision nanomedicine 2022

<img src=” https://s3.amazonaws.com/production.scholastica/article/37505/large/prnano_812022ga_2.jpg?1661898072”> Ionically complexed nanoparticles were prepared from an anionic polysaccharide drug, heparin, entrapped by a positively charged chitosan polysaccharide. In this study, the encapsulation of heparin was studied to optimize properties needed for its oral drug delivery. Chitosan, ...

Journal: :Gut 1996
E C Van Os B J Zins W J Sandborn D C Mays W J Tremaine D W Mahoney A R Zinsmeister J J Lipsky

BACKGROUND 6-Mercaptopurine and its prodrug azathioprine are effective medications for refractory inflammatory bowel disease. However, use of these drugs has been limited by concerns about their toxicity. Colonic delivery of azathioprine may reduce its systemic bioavailability and limit toxicity. AIM To determine the bioavailability of 6-mercaptopurine after administration of azathioprine via...

2003
Sachan R

Oral route is the easiest and most convenient route for drug administration. Oral drug delivery systems being the most cost-effective and leads the worldwide drug delivery market. The major problem in oral drug formulations is low and erratic bioavailability, which mainly results from poor aqueous solubility. This may lead to high interand intra subject variability, lack of dose proportionality...

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