BACKGROUND Misoprostol is a prostaglandin E(1) analogue that has been used for medical abortion. We conducted this prospective study to compare the efficacy of vaginal misoprostol for abortion in women at a gestational age of <42 days and in women at a gestational age of 42-56 days. METHODS A total of 160 women seeking medical termination of a pregnancy of <56 days were enrolled in the study....

Methods A 27-year-old woman with gravida 2, parity 1, was admitted to our unit because of twin pregnancy at 12th weeks' gestation. Ultrasound examination was performed using a 7. 5 MHz transvaginal probe with two-dimensional ultrasonography. The crown-rump length measurements were 49 mm and 51 mm respectively, consistent with 12 weeks of gestation. The fetal chests were fused and only one fetal...

OBJECTIVE To describe the use of mifepristone in combination with buccal misoprostol in women undergoing an early medical abortion (EMA) in Australia. DESIGN, SETTING AND PARTICIPANTS Retrospective, observational study of 13,345 EMAs (gestational age ≤ 63 days) conducted at 15 Marie Stopes International Australia clinics between 1 September 2009 and 31 August 2011. INTERVENTION Oral mifepri...

BACKGROUND Misoprostol is widely used in obstetrics and gynaecology for medical abortion, cervical priming and induction of labour. To aid the design of effective and safe regimens, we have investigated the pharmacokinetic parameters after the vaginal or sublingual administration of repeated doses of 400 microg of misoprostol. METHODS Women undergoing termination of pregnancy by suction evacu...