The oral rehydration therapy is the keystone of National Diarrhoeal Disease Control Programme. The packets of oral rehydration salts (ORS) are available at the Primary health centres as well as in chemist shops. There are depot holders of ORS packets in the community too. Most of the times the health care workers do not emphasise the role, benefits and method of preparation of ORS. As a result ...

OBJECTIVE To determine whether adding L-alanine to the glucose based oral rehydration solution recommended by the World Health Organisation would improve its efficacy in treating acute diarrhoea. DESIGN Randomised double blind controlled trial of oral rehydration solution containing L-alanine and glucose. SETTING Inpatient service of a hospital treating diarrhoea. PATIENTS 97 Male patient...

BACKGROUND Based on European recommendations of ESPGHAN/ESPID from 2008, first line therapy for dehydration caused by acute gastroenteritis (AGE) is oral rehydration solution (ORS). In case of oral route failure, nasogastric tube enteral rehydration is as efficient as intra-venous rehydration and seems to lead to fewer adverse events. The primary objective was to describe rehydration strategies...

Oral rehydration therapy prevents death in acute watery diarrhoea except in the most severe 1-3% of cholera cases. If started at the onset of illness, weakness, orthostasis, muscle cramps, lethargy, and other symptoms of a contracted circulating blood volume are entirely prevented.' Poor countries have rapidly expanded their use of this practical and inexpensive treatment2 while it has been lar...

confirmed these findings and showed a 19% reduction in stool output with oral rehydration solution containing glucose and glycine compared with the standard oral rehydration solution.6 On the other hand, results from six studies in children under 3 years with acute diarrhoea, including diarrhoea associated with rotavirus, showed that the addition of glycine and, in some studies, glycyl-glycine ...

In situ perfusion of rat intestine was used to evaluate the effect of bicarbonate on the efficacy of a low sodium (35 mmol/l) glucose-electrolyte oral rehydration solution in normal and cholera toxin-treated rat small intestine. In normal intestine, absorption of water was greater (108 (8.1) microliters/min/g; p less than 0.01) and sodium secretion less (-4.3 (0.3) mumol/min/g; p less than 0.01...