نتایج جستجو برای: organ damage

تعداد نتایج: 320478  

Journal: :Respiratory Physiology & Neurobiology 2013
Mariana C. Souza Johnatas D. Silva Tatiana A. Pádua Vera Luiza Capelozzi Patricia R.M. Rocco Maria das Graças Henriques

Severe malaria is characterised by cerebral oedema, acute lung injury (ALI) and multiple organ dysfunctions, however, the mechanisms of lung and distal organ damage need to be better clarified. Ninety-six C57BL/6 mice were injected intraperitoneally with 5×10(6)Plasmodium berghei ANKA-infected erythrocytes or saline. At day 1, Plasmodium berghei infected mice presented greater number of areas w...

2013
Saskia M Rombach Carla EM Hollak Gabor E Linthorst Marcel GW Dijkgraaf

BACKGROUND The cost-effectiveness of enzyme replacement therapy (ERT) compared to standard medical care was evaluated in the Dutch cohort of patients with Fabry disease. METHODS Cost-effectiveness analysis was performed using a life-time state-transition model. Transition probabilities, effectiveness data and costs were derived from retrospective data and prospective follow-up of the Dutch st...

Journal: :Journal of Evolution of Medical and Dental Sciences 2017

Journal: :Hypertension research : official journal of the Japanese Society of Hypertension 2004
Atsuhisa Sato Takao Saruta

In recent years, it has been clarified that aldosterone can directly damage various organs, such as the heart, blood vessel, and kidneys, via non-epithelial mineralocorticoid receptors, independent of changes in blood pressure. Anti-aldosterone drugs have been clinically reported to be useful for their organ-protecting effects. The fact that these effects have been considered important for almo...

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