Crohn's disease is a chronic inflammatory bowel disease that can involve the whole gastrointestinal tract. The orofacial manifestation of Crohn's disease, which is rare, can develop irrespective of intestinal involvement. These orofacial lesions are often misdiagnosed as simple oral ulcers. Corticosteroids are the mainstay of therapy for orofacial Crohn's disease. However, infliximab, the chime...

Objective: To review the available literature on orofacial pain. Material and Methods: This literature review was performed to elucidate information pertaining to orofacial pain from various medical databases. Result: Pain of any origin compromises on an individual’s quality of life. The prevention and management of pain is an important aspect of health care. This multidimensional phenomenon re...

BACKGROUND In a retrospective study, risk factors for complications after the bridging of mandibular defects using reconstruction plates were reviewed. Especially the loosening of the plate-screw-mandible complex should be analyzed with a finite element model in order to reduce plate complications in future. PATIENTS AND METHODS We examined 60 patients who underwent a treatment with reconstru...

The need for this document reflects the often controversial history of the field, with many unfounded claims and “facts” that have served to negatively impact many in dentistry and other disciplines toward the field and those who practice orofacial myology. By addressing facts and fictions here, you should be better equipped to represent your discipline in a manner consistent with the scientifi...

Since dental/orofacial injuries were the commonest type of injuries sustained during participation in sports activities in the 1980s, when it was apparent that one third of dental injuries was due to sporting involvement, with the remainder being due to accidents, especially at home, the role of the dental profession in relation to dental/orofacial sports injuries became very important. This ha...

mothers exposed to antiepileptic drugs (aeds) are at high risk to born babies with orofacial malformations such as cleft lips. about 9 percent of congenital abnormalities in babies of mothers with epilepsy relates to orofacial abnormalities. maintaining safe antiepileptic drugs for millions of mothers with epilepsy is very important. researches show that new aeds have less side effects than the...

OBJECTIVE To establish the role of TRPV1 receptor in the antinociceptive effect of natural alkamides (i.e. affinin, longipinamide A, longipenamide A and longipenamide B) isolated from Heliopsis longipes (A. Gray) S.F. Blake and some related synthetic alkamides (i.e. N-isobutyl-feruloylamide and N-isobutyl-dihydroferuloylamide). METHODS The orofacial formalin test was used to assess the antino...

OBJECTIVES To present descriptive epidemiology of Orofacial Clefts and to determine the association of syndromic forms with antenatal high-risk conditions, preterm birth, and comorbidities among nested-series of cases. METHODS A study of nested-series of cases was conducted. Frequencies of cleft type, associated congenital anomalies, syndromic, non-syndromic and multiple malformation forms, a...

In this study, the effects of subcutaneous (SC) injection of pilocarpine (a cholinomimetic agent) and atropine (a muscarinic receptors antagonist) were investigated on a tonic model of orofacial pain in rats. The contribution of the endogenous analgesic opioid system was assessed using naloxone (an opioid receptors antagonist). Tonic orofacial pain was induced by SC injection of a diluted forma...

1. LIST OF ORIGINAL PUBLICATIONS / 10 2. INTRODUCTION / 11 3. REVIEW OF THE LITERATURE / 12 3.1. Bruxism / 12 3.1.1. PubMed / 12 3.1.2. Definitions of bruxism / 12 3.1.3. Detecting sleep bruxism: electromyography (EMG) and polysomnography (PSG) / 13 3.1.4. Detecting sleep bruxism: ambulatory EMG / 14 3.1.5. Detecting sleep/awake bruxism: self-reports and clinical guidelines / 14 3.1.6. Detectin...