The development of oral rehydration solutions (ORSs) has been one of the important therapeutic advances of this century. The optimal formulation, however, of ORSs for both cholera and other infective diarrhoeas is still debated. Part of the problem in developing ORSs has been the lack of adequate test systems for the assessment of new formulations before clinical trial. We have developed a jeju...

JAK inhibitors (JAKi), a major advance in AA therapy may not restore hair follicle’s (HF) physiological immune privilege (IP). Yet, HF IP collapse is required for to develop, while HFs with intact/restored are relatively AA-resistant. Therefore, additional therapeutics needed that target pathogenic pathways unaffected by JAKi. Namely, NKG2D on T and NK cells activated the epithelial distress si...

Baculoviruses are double-stranded DNA entomopathogenic viruses that infect predominantly insects of the order Lepidoptera. Research in last decade has started to disentangle mechanisms underlying insect-virus interaction, particularly focusing on effects baculovirus infection host's physiology. Among crucial physiological functions, olfaction a key role reproductive tasks, food source detection...

The incidence of surgical site infection differs among operating rooms (ORs). However, cost effectiveness interventions targeting ORs depends on counts. purpose this study was to quantify the inequality counts ORs. We performed a single-centre historical cohort elective cases spanning 160-week period from May 2017 2020, identifying within 90 days using International Classification Diseases, Ten...

Abstract Objective Coronavirus Disease-19 (COVID-19) has become a global pandemic, and mental health of children parents are affected by confinement in home. Since the outbreak COVID-19 is still pandemic currently, it important to examine how changes children’s behaviors parent–child relationship affect parental anxiety during this difficult time. Methods A cross-sectional online investigation ...

Multiple primary and eutectic intermetallic compounds (IMCs) often form during the solidification of multicomponent magnesium alloys. Here, we comprehensively explore formation in Mg-4Sn-3Al-1.5Zn-0.6Mn (wt%) as-cast alloy, comparison with Mg-3Al-1Zn-0.3Mn, to better understand Mg 2 Sn complex multiphase how it affects other IMCs. Various IMCs formed at different stages solidification: τ-AlMn A...

Background Oral rehydration solution (ORS) has the potential to avert deaths from diarrheal diseases. Nevertheless, in poor nations only about half of children with diarrhea receive ORS. Since 2014, India run an annual Intensified Diarrhea Control Fortnight increase ORS treatment. A key element plan is free distribution over 100 million homes young children. Methods We compared usage reported 2...

To understand the effects of lattice mismatch on heteroepitaxial growth, we have studied equilibrium structure and orientation relationships (ORs) FCC films grown epitaxially substrates, using molecular dynamics simulations in conjunction with embedded atom method potentials. Three film/substrate systems been investigated, namely: Ag Cu, Ni Pb Al. These cover a significant range mismatch, from ...

BACKGROUND Oculorespiratory syndrome (ORS) after influenza vaccination has many features of an allergic reaction. METHODS The objective of the study was to estimate the recurrence rate of ORS after receipt of either of 2 influenza vaccines available in Canada for the 2002-2003 influenza season in individuals who experienced ORS in 2000 or 2001. We designed a randomized, crossover, double-blin...

BACKGROUND More than 500 000 young children die from dehydration caused by severe diarrhea each year, globally. Although routine use of oral rehydration solution (ORS) could prevent almost all of these deaths, ORS utilization remains low in many low-income countries. Previous research has suggested that misperceptions among caregivers may be an obstacle to wider use of ORS. METHODS To better ...