Periodontic-orthodontic interactions are mutually beneficial. Combined periodontic and orthodontic treatment can greatly enhance periodontal health and dentofacial esthetics. Adjunctive orthodontic management of pathological tooth migration has unique effects in subjects with moderate to advanced periodontitis. Orthodontic treatment should only be undertaken with healthy periodontium or healthy...

The lingual orthodontic therapy though started in 1972, could not be popular till the beginning of 1990. In Nepal it does not have a history of more than a year. It is started in Dhulikhel Hospital for the first time in Nepal. Usually orthodontic therapy is meant for putting braces on the labial surface of the teeth which is called labial orthodontic system. Lingual orthodontic system is a pure...

the overall rate of atrial pacing lead dislodgement is estimated to be about 3%. these leads are generally repositioned via a second operation through opening the pacemaker pocket. some operators have introduced percutaneous techniques using snare system or deflectable catheters for this purpose. in this article we present our experience with five cases of percutaneous lead repositioning. three...

background and aims. this in vitro study was designed to evaluate the effect of composite resin types and orthodontic debonding pliers on the amount of adhesive remnants and enamel damages using a novel method of measurement. materials and methods. 120 extracted human premolars were randomly divided into four groups (n = 30). the standard edgewise metallic brackets were bonded to the teeth with...

OBJECTIVE To investigate the use of canalith repositioning manoeuvres and vestibular rehabilitation (VR) by GPs and to assess reasons for not using these techniques in patients with vertigo. DESIGN Online survey. SETTING GPs in the western and central part of the Netherlands. SUBJECTS AND METHOD Of GPs, 1169 were approached to participate in the survey. A sample of 426 GPs filled out the ...

Orthodontics is based on tooth movement through bone resulting from the application of mechanical forces. The bone remodeling takes place through an inflammatory process associated with pain or discomfort. Orthodontic pain is the most frequent complaint of the patients undergoing orthodontic therapy. The lengthy duration of treatment along with frequent pain due to the orthodontic appliances of...

Whether gene repositioning to the nuclear periphery during differentiation adds another layer of regulation to gene expression remains controversial. Here, we resolve this by manipulating gene positions through targeting the nuclear envelope transmembrane proteins (NETs) that direct their normal repositioning during myogenesis. Combining transcriptomics with high-resolution DamID mapping of nuc...

Finding new uses for existing drugs, or drug repositioning, has been used as a strategy for decades to get drugs to more patients. As the ability to measure molecules in high-throughput ways has improved over the past decade, it is logical that such data might be useful for enabling drug repositioning through computational methods. Many computational predictions for new indications have been bo...

BACKGROUND Pressure ulcers/injuries (PrUs), a critical concern for nursing homes (NH), are responsible for chronic wounds, amputations, septic infections, and premature deaths. PrUs occur most commonly in older adults and NH residence is a risk factor for their development, with at least one of every nine U.S. NH residents experiencing a PrU and many NHs having high incidence and prevalence rat...