Cherubism is a self-limiting non-neoplastic autosomal dominant fibro-osseous syndrome of the jaws. It is occasionally manifested before the age of two years. It occurs in children and more often in boys. It is characterized by notable clinical bilateral swelling of the cheeks due to a bony enlargement of the jaws that impart a characteristic 'cherubic' look. Regression occurs in the course of p...

Cherubism is a rare disorder with autosomal dominant inheritance. It is classified as a benign fibro-osseous lesions and may involve either facial bone. Its typical dentofacial deformities are caused by mutations in the SH3BP2 gene. The protein encoded by SH3BP2 had a significant role in the regulation of osteoblasts and osteoclasts. Accordingly with the radiological findings, differential diag...

Surgery on the dentoalveolar process combined with orthodontic treatment was emphasized as an alternative method for reducing the treatment time and improving the orthodontic treatment on post-adolescent and adult patients. This combined treatment facilitates and accelerates orthodontic tooth movement. This article reviews the clinical practice in surgery-assisted orthodontic treatment in relat...

Figure Legend: Figure 1 Bone Fibro-osseous lesion in the femur of a female B6C3F1/N mouse from a chronic study. Figure 2 Bone Fibro-osseous lesion in a female B6C3F1/N mouse from a chronic study. This fibro-osseous lesion shows replacement of bone by fibrovascular tissue. Figure 3 Bone Fibro-osseous lesion in a female B6C3F1/N mouse from a chronic study. Figure 4 Bone Fibroosseous lesion in a f...