Widespread use of Mg-Zn-Ca alloys in clinical orthopedic practice requires improvement their mechanical properties—in particular, ductility—and enhancement bioactivity for accelerated osteoreconstruction. The alloy was studied two structural states: after homogenization and equal-channel angular pressing. Immersion potentiodynamic polarization tests showed that the corrosion rate not increased ...

Identifying a reliable and effective cytokine or growth factor group has been the focus of stem cell osteogenic induction studies. Concentrated growth factors (CGFs) as the novel generation of platelet concentrate products, appear to exhibit a superior clinical and biotechnological application potential, however, there are few studies that have demonstrated this effect. This study investigated ...

Recently, the first clinical reports on bone regeneration by two recombinant human bone morphogenetic proteins (rhBMPs), BMP-2 and BMP-7 (also named osteogenic protein-1, OP-1) have been published (1-4). Although both BMPs were able to support bone regeneration, a significant variation in individual response was observed with both proteins. Animal studies and laboratory experiments reveal a num...