A huge number of chemicals are produced and used in the world, and some of them can have negative effects on the reproductive health of workers. To date, most chemicals and work environments have not been studied for their potential to have damaging effects on the workers' reproductive system. Because of the lack of information, many workers may not be aware that such problems can be related to...

The use of agricultural chemicals is an important aspect of animal production. Animal scientists have played an active and varied role in the recent and rapidly developed use of these chemicals. Although approval to use agricultural chemicals has always been based on both efficacy and end point residues, increased consumer concerns during the past one and one-half decades about the safety of th...

Neurodevelopmental disabilities, including autism, attention-deficit hyperactivity disorder, dyslexia, and other cognitive impairments, affect millions of children worldwide, and some diagnoses seem to be increasing in frequency. Industrial chemicals that injure the developing brain are among the known causes for this rise in prevalence. In 2006, we did a systematic review and identified five i...

Every day, the United States alone uses or imports about 42 million pounds of synthetic chemicals. There are more than 84 000 compounds approved for commercial use in the United States, most of which have never been tested for toxicity. A 2011 policy statement issued by the American Academy of Pediatrics acknowledges that the large quantities of chemicals that enter commerce could be harmful to...

PURPOSE Tannery workers are exposed to hazardous chemicals. Tannery work is outsourced to newly industrialized countries (NICs) where attention into occupational health hazards is limited. In this study, we investigated the skin exposure to hazardous chemicals in tannery workers and determined the prevalence of occupational skin diseases (OSDs) at tanneries in a NIC. METHODS A cross-sectional...

There is continuing controversy, extending into regulatory matters, over the significance to human health of positive results in carcinogenicity studies in animals using the gavage technique as the route of exposure. Our review of a nonrandom sample of 117 chemicals or chemical processes listed as known or reasonably anticipated to be carcinogenic in the National Toxicology Program's Third Annu...

BACKGROUND Human exposure to parabens and other antimicrobial chemicals is continual and pervasive. The hormone-disrupting properties of these environmental chemicals may adversely affect human reproduction. OBJECTIVE We aimed to prospectively assess couples' urinary concentrations of antimicrobial chemicals in the context of fecundity, measured as time to pregnancy (TTP). METHODS In a pros...

BACKGROUND Fluoride additives contain metal contaminants that must be diluted to meet drinking water regulations. However, each raw additive batch supplied to water facilities does not come labeled with concentrations per contaminant. This omission distorts exposure profiles and the risks associated with accidents and routine use. OBJECTIVES This study provides an independent determination of...

The fact that food can produce adverse effects on behavior has long been known, but efforts to systematically evaluate foods and other chemicals for such effects are a more recent pursuit. The fields that have evolved to assess these effects have come to be termed behavioral toxicology when effects on mature organisms are examined’ and behavioral teratology when the effects on developing organi...

Together with taste and smell, oral sensations of touch, temperature, chemical irritation and pain play an important role in determining food flavor. Trigeminal sensations are mediated by sensory fibers innervating the oral mucosa that project via the lingual nerve to reach the brainstem trigeminal complex, with extensive terminations in subnucleus caudalis (Vc) (Carstens et al., 1995). Neurons...