نتایج جستجو برای: outer hair cells

تعداد نتایج: 1459809  

Journal: :Proceedings of the National Academy of Sciences 1993

Journal: :Proceedings of the National Academy of Sciences 1999

2017
Guillaume Duret Fred A Pereira Robert M Raphael

The motor protein prestin is a member of the SLC26 family of anion antiporters and is essential to the electromotility of cochlear outer hair cells and for hearing. The only direct inhibitor of electromotility and the associated charge transfer is salicylate, possibly through direct interaction with an anion-binding site on prestin. In a screen to identify other inhibitors of prestin activity, ...

Journal: :Journal of the Association for Research in Otolaryngology 2002

2015
Kristina E Froud Ann Chi Yan Wong Jennie M E Cederholm Matthias Klugmann Shaun L Sandow Jean-Pierre Julien Allen F Ryan Gary D Housley

The dynamic adjustment of hearing sensitivity and frequency selectivity is mediated by the medial olivocochlear efferent reflex, which suppresses the gain of the 'cochlear amplifier' in each ear. Such efferent feedback is important for promoting discrimination of sounds in background noise, sound localization and protecting the cochleae from acoustic overstimulation. However, the sensory driver...

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