OBJECTIVE Ovarian hyperstimulation syndrome (OHSS) is a serious iatrogenic condition, predominantly related to the hormone used to induce oocyte maturation during IVF treatment. Kisspeptin is a hypothalamic neuropeptide that has recently been demonstrated to safely trigger final oocyte maturation during IVF treatment even in women at high risk of OHSS. However, to date, the safety of kisspeptin...

BACKGROUND Approximately 20% of oocytes are classified as immature and discarded following intracytoplasmic sperm injection (ICSI) procedures. These oocytes are obtained from gonadotropin-stimulated patients, and are routinely removed from the cumulus cells which normally would mature the oocytes. Given the ready access to these human oocytes, they represent a potential resource for both clinic...

During gonadal maturation the females of Steindachnerina insculpta, a teleost of the Furnas reservoir, Minas Gerais, Brazil, show low hepatosomatic and high gonadossomatic indexes, suggesting possible transference of hepatic substances to the ovaries. In comparison to the resting phase, in the maturation/ mature one the hepatocytes show greater development of both smooth and rough endoplasmic r...

It is known that the follicular selection and final stages of follicular maturation are equal if not more dependent on low circulating levels of LH.In addition to stimulating production of thecal androgens as substrate for estrogen synthesis, LH stimulates granulose cell via LH receptors induced by FSH and estrogen in larger but not smaller follicles. The data from numerous assisted reproductio...

vascularization of the follicle may play a role in its maturation and aspirin seems to increase this vascularization.in this investigation we have studied the effects of low-dose aspirin on ovarian and uterine response, implantation and pregnancy rates in patients undergoing intracytoplasmic sperm injection (icsi). this prospective semirandomized, double-blind, placebo-controlled study was unde...

Abstract Study question Whether follicular extracellular vesicles of older women interfere with the quality oocytes. Summary answer OLD-EVs induced oxidative stress in oocytes and inhibited oocyte maturation by increasing abnormal mitochondria distribution spindle rates. What is known already Ovary a critical regulator female fertility source With modern tendency delaying childbearing, ovarian ...

The aims of the present study were to assess the effects of cysteamine as an anti-oxidant on the rate of in vitro maturation (IVM) of buffalo oocytes (experiment 1), and their viability and nuclear status following vitrification (experiment 2). Immature oocytes with compact cumulus cells obtained from the ovaries of slaughtered animals were harvested and then cultured in the maturation medium w...

Long-term exposure to low temperatures during adult maturation might decrease fertility after cold recovery as a consequence of carry-over effects on reproductive tissues. This pattern should be more pronounced in tropical than in temperate species as protective mechanisms against chilling injuries are expected to be more effective in the latter. We initially determined the lower thermal thresh...

introduction: this study was performed to investigate the effect of vitrification procedure using ethyleneglycol as cryoprotectant on the follicular morphology of neonatal ovarian tissue of mouse after thawing andautotransplantation. material and methods: ovaries from 3 weeks neonate nmri mice were excised then vitrified in asolution of dmem medium containing ficol 70, sucrose, acetanied and et...

Background This research was conducted to assess preantral follicle development in fibrin alginate matrix following ovarian tissue vitrification MaterialsAndMethods Ovaries of 13-day-old NMRI female mice were removed and placed in control and vitrification groups. Vitrification group ovaries were transferred in media containing ethylene glycol, dimethyl sulphoxide, and sucrose then were plunged...