نتایج جستجو برای: overactive bladder
تعداد نتایج: 57721 فیلتر نتایج به سال:
OBJECTIVES To investigate the effects of various muscarinic acetylcholine receptor (mAChR) antagonists, including selective M2 and M3 mAChR antagonists, on bladder overactivity. It has been proposed that the urothelium modulates the activity of bladder afferent pathways. However, the differential roles of mAChR subtypes in local bladder afferent activation remain unclear. METHODS Cystometry w...
The activation of the TRPM8 channel, a member of the large class of TRP ion channels, has been reported to be involved in overactive bladder and painful bladder syndrome, although an endogenous activator has not been identified. In this study, N-(3-aminopropyl)-2-{[(3-methylphenyl) methyl]oxy}-N-(2-thienylmethyl)benzamide hydrochloride salt (AMTB) was evaluated as a TRPM8 channel blocker and us...
INTRODUCTION Restless genital syndrome (ReGS) is characterized by unwanted, unpleasant genital sensations, restless legs, and/or overactive bladder, as well as neuropathy of the dorsal nerve of the clitoris. So far, ReGS has only been reported in females. AIM To report the occurrence of ReGS in two males. METHODS Two males with unwanted genital sensations presented in our clinic. In-depth i...
1Department of Urology, Radboud University Nijmegen MC, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands 2Department of Urology, University of Porto, 4200-319 Porto, Portugal 3Department of Continence Medicine, The University of Tokyo Graduate School of Medicine, Tokyo 113-8655, Japan 4Department of Urology, College of Medicine, University of Illinois at Chicago, 840 SouthWood Street, Chicago, ...
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