Using both in vitro (hippocampal synaptosomes in superfusion) and in vivo (microdialysis) approaches we investigated whether and to what extent β amyloid peptide 1-40 (Aβ 1-40) interferes with the cholinergic modulation of the release of glycine (GLY) in the rat hippocampus. The nicotine-evoked overflow of endogenous GLY in hippocampal synaptosomes in superfusion was significantly inhibited by ...

We consider a fluid queue fed by a superposition of n homogeneous on-off sources with generally distributed onand off-periods. We scale buffer space B and link rate C by n, such that we get nb and nc, respectively. Then we let n grow large. In this regime, the overflow probability decays exponentially in the number of sources n; we specifically examine the situation in which also b is large. We...

BACKGROUND Endothelin (ET)-1 and norepinephrine (NE) are involved in myocardial ischemia/reperfusion injury. We investigated the role of ET-1 in ischemia/reperfusion-induced NE overflow and cardiac dysfunction using a selective ET(A) receptor antagonist (ABT-627), a selective ET(B) receptor antagonist (A-192621), and the spotting lethal (sl) rat, which carries a naturally occurring deletion in ...

Events such as loss packets in queuing systems and bankruptcy probabilities for insurance companies are rare but consequential. The likelihood of such events can often be linked to the maximum of a stochastic process. We refer to such quantities as overflow probabilities—due to their connection to queues. Current Monte Carlo algorithms for efficient evaluation of overflow probabilities often as...

A physical model of gabion overflow dams was studied to determine the velocity profile and Reynolds shear stress. Physical tests were done under two different conditions of dam crest, overflow dams with impermeable and with permeable crests. Instantaneous velocity components over dam crest were measured by an ADV (Acoustic Doppler Velocimeter) instrument. This instrument is capable of measuring...

Buffer overflow attacks have been causing serious security problems for decades. With more embedded systems networked, it becomes an important research problem to defend embedded systems against buffer overflow attacks. In this paper, we propose the Hardware/Software Address Protection (HSAP) technique to solve this problem. We first classify buffer overflow attacks into two categories (stack s...

Driver distraction and safety concerns have been identified for new highway logo sign configurations. This study assessed driver perception of logo signs and distraction under nine-panel, overflow-combination, or standard six-panel formats. A nine-panel sign has nine business panels within a single sign; a six-panel sign has six panels within a sign; an overflow-combination consists of a standa...

Theories of consciousness can be separated into those that see it as cognitive in nature, or as an aspect of cognitive functioning, and those that see consciousness as importantly distinct from any kind of cognitive functioning. One version of the former kind of theory is the higherorder-thought theory of consciousness. This family of theories posits a fundamental role for cognitive states, hig...

Instantiation overflow is the property of those second order types for which all instances of full comprehension can be deduced from instances of atomic comprehension. In other words, a type has instantiation overflow when one can type, by atomic polymorphism,"expansion terms"which realize instances of the full extraction rule applied to that type. This property was investigated in the case of ...