Cockayne syndrome (CS) is a multisystem degenerative disorder divided in 3 overlapping subtypes, with continuous phenotypic spectrum: CS2 being the most severe form, CS1 classical form and CS3 late-onset form. Failure to thrive growth difficulties are among consistent features of CS, leaving affected individuals vulnerable numerous medical complications, including adverse effects undernutrition...

Continuous blood volume monitoring (CBVM) is believed to be a promising method for making the determination of patients' "dry weight" more objective, and ultrafiltration (UF) control more appropriate. Although blood volume response to UF and the interrelation between blood volume changes and changes in hemodynamic parameters are highly individual, certain principles of this response and interre...

The properties of blood and the relative ease of access to which it can be retrieved make it an ideal source to gauge different aspects of homeostasis within an individual, form an accurate diagnosis, and formulate an appropriate treatment regime. Tests used to determine blood parameters such as the erythrocyte sedimentation rate, hemoglobin concentration, hematocrit, bleeding and clotting time...