New materials have significant impact on development of new methods and instrumentation for chemical analysis. From the discovery of carbon nanotubes in 1991, single and multi-walled carbon nanotubes (SWCNTs and MWCNTs) -due to their high adsorption and desorption capacitieshave been employed as sorption substrates in solid-phase extraction for the preconcentration of heavy metals from diverse ...

An automated multi-channel continuous-flow analyzing system was constructed for the rapid measurement of both the tota} amino acid content and the L-gtutamate content of green tea infusions. i.-Glutamate in samples was oxidized and deaminated enzymaticatly in a channel -'ith a mini-reactor that "'as packed with i.-glutamate oxidase immebilized on glass beads, and the evolyed ammonium ions were ...

In this communication, we use first-principles based multi-level computational methods to predict the crystal structure of Li4C6O6, the key intermediate material that can be oxidized to Li2C6O6 or reduced to Li6C6O6. This predicted structure leads to an X-ray diffraction (XRD) pattern in good agreement with experiment, validating the predicted structure. With this structure in hand one can proc...

Although oxidized lipoproteins may play an important role in the progression of atherosclerosis, no report has mentioned the significance of oxidized lipoprotein (a) (Lp[a]) in the pathogenesis of cardiovascular disease. Initially, we compared the mitogenic actions of Lp(a) and oxidized Lp(a) on human vascular smooth muscle cells (VSMC). Lp(a) significantly stimulated the growth of human VSMC i...

OBJECTIVE To investigate binding of C-reactive protein (CRP) and annexin A5, 2 proteins with high affinity for negatively charged phospholipids, to oxidized low-density lipoprotein (LDL) and the consequences of these interactions for subsequent binding of oxidized LDL to monocyte/macrophage-like U937 cells. METHODS AND RESULTS We found that CRP and annexin A5 at physiological concentrations b...

Oxidative stress is correlated with the incidence of several diseases such as atherosclerosis and cancer, and oxidized biomolecules have been determined as biomarkers of oxidative stress; however, the detailed molecular relationship between generated oxidation products and the promotion of diseases has not been fully elucidated. In the present study, to clarify the role of serum oxidation produ...

in an environmentally benign solventless system, alcohols are rapidly oxidized to carbonyl compounds using hexamethylenetetramine-bromine on wet alumina under microwave irradiation.

Oxidation of LDL is an important factor in the development of atherosclerosis. However, the mechanisms by which oxidized LDL exerts its atherogenic actions are poorly understood. In the present work, we show that oxidized LDL stimulates phospholipase D (PLD) activity in mouse peritoneal macrophages and that this effect increases with the degree of LDL oxidation. Oxidative modification of LDL re...