ADDRESS: 555 University Avenue, Toronto, Ontario, Canada. and dihydrostreptomycin. Ann. Otob. Rhin. & Laryng., 62:101, 1953. 33. Winston, J. : Clinical problems pertaining to neurotoxicity of streptomycin group of drugs. Arch. Otolaryng., 58:55, 1953. 34. Jongkees, L. B. W., and Hulk, J. : The action of streptomycin on vestibular function. Acta oto-laryng., 38:225, 1950. 35. Kern, A. R., and Wi...

BACKGROUND The traditional oxygen delivery methods for oxygen therapy are continuous flow oxygen (CFO) and demand oxygen delivery (DOD); however, oxygen waste is considerable in CFO, while DOD is uncomfortable for patients. Synchronized DOD (SDOD), which was designed to overcome the drawbacks of both CFO and DOD, supplies oxygen according to the patient's breathing pattern and the desired oxyge...

It was recently established that supplemental oxygen administration significantly enhances memory formation in healthy young adults. In the present study, a double-blind, placebo-controled design was employed to assess the cognitive and physiological effects of subjects' inspiration of oxygen or air (control) prior to undergoing simple memory and reaction-time tasks. Arterial blood oxygen satur...

Administration of nitrous oxide is useful for providing sedation and analgesia. The therapeutic range for nitrous oxide is 20-30%. Several oxygen treatment devices have been used for administering nitrous oxide, but little is known about the concentrations of nitrous oxide and oxygen delivered to the trachea. We have studied this, using an analogue lung model, with several oxygen therapy device...

Oxygen has been widely used in neonatal resuscitation for about 300 years. In October 2010, the International Liaison Committee on Neonatal Resuscitation released new guidelines. Based on experimental studies and randomized clinical trials, the recommendations on evaluation and monitoring of oxygenation status and oxygen supplementation in the delivery room were revised in detail. They include:...

An oxygen-enriched atmosphere enhances the potential for operating-room fires. We thus determined oxygen concentrations at various facial landmarks during oxygen administration via nasal cannulae. Thirteen supine volunteers were draped similarly to patients undergoing a cervical-node biopsy. Oxygen was delivered in random order through nasal cannulae at rates of 2, 4, and 6 l x min(-1). Oxygen ...

Modern clinical use of supplemental oxygen supposes that: (1) exposure to F(IO)(2) < or = 60% is without adverse effects, (2) an individual at risk of developing arterial hypoxemia can be protected by administering high F(IO)(2), and (3) routine administration of supplemental oxygen is useful, harmless, and clinically indicated. There is now substantial evidence that none of those 3 supposition...