نتایج جستجو برای: oxygen deficiency
تعداد نتایج: 342153 فیلتر نتایج به سال:
OBJECTIVES OBJECTIVES The effect of cortical spreading depression (CSD) on extracellular K(+) concentrations ([K(+)](e)), cerebral blood flow (CBF), mitochondrial NADH redox state and direct current (DC) potential was studied during normoxia and three pathological conditions: hypoxia, after NOS inhibition by L-NAME and partial ischemia. METHODS A SPECIAL DEVICE (MPA) WAS USED FOR MONITORIN...
The crystal structure of zirconium oxide nanoparticles was refined by the Rietveld analysis of synchrotron X-ray powder diffraction data measured at 298 K. In the nanoparticles, two phases of tetragonal ZrO(2 - delta) (average particle size: 11 +/- 2 nm) and monoclinic ZrO2 (average particle size: 24 +/- 4 nm) existed, where the weight fractions were estimated to be 84.9 and 15.1 wt%, respectiv...
Loeffler I, Wolf G. Morg1 heterozygous deficiency ameliorates hypoxia-induced acute renal injury. Am J Physiol Renal Physiol 308: F511–F521, 2015. First published December 30, 2014; doi:10.1152/ajprenal.00236.2014.—Acute kidney injury is a common complication of critically ill patients and may occur as a result of various factors and coexisting previous illnesses. Some pathophysiological respon...
Hypoglycemia, a complication of insulin or sulfonylurea therapy in diabetic patients, leads to brain damage. Furthermore, glucose replenishment following hypoglycemic coma induces neuronal cell death. In this study, we investigated the molecular mechanism underlying glucose deficiency-induced cytotoxicity and the protective effect of d-β-hydroxybutyrate (D-BHB) using SH-SY5Y cells. The cytotoxi...
Abstract Hypoxia in coastal seas is a severe threat to marine ecosystems, with the Baltic Sea exhibiting largest hypoxic areas worldwide. While perennial oxygen deficiency deep basins component of environmental assessments, seasonal shallow not routinely assessed. Current measurements alone cannot provide spatio-temporal resolution needed for highly dynamic deficiency, making estimations on its...
Developing cathodes capable of working at intermediate temperatures (IT) is key to improving solid oxide fuel cells’ (SOFC) durability, ease operation, and manufacturing cost reduction. BaFeO3-δ (BFO)-based perovskites are ideal candidates because their fast kinetics, which due the mixed conduction oxygen vacancies electron-holes. Thus, maximizing vacancy hole concentration can further enhance ...
Anemia is a common complication of chronic kidney disease. Although mechanisms involved in the pathogenesis of renal anemia include chronic inflammation, iron deficiency, and shortened half-life of erythrocytes, the primary cause is deficiency of erythropoietin (EPO). Serum EPO levels in patients with chronic kidney disease are usually within the normal range and thus fail to show an appropriat...
Metal ions can exist in several forms. Ion-exchange plays an important role in modern analytical chemistry. Transition metals can be separated using either anion or cation exchange chromatography, depending on the choice of complexing agent used in the eluent. Iron deficiency is the most common of nutritional anemia in human beings. It is also an essential component of myoglobin, cytochomes, ca...
Iron (Fe) is an essential metal that plays important roles in physiology. Iron is responsible for a vast array of biochemical reactions, including supporting cell division, oxygen transport and mitochondrial function [1,2]. Iron deficiency is the most prevalent single nutrient deficiency worldwide [2,3] and results in anemia, retarded growth, fatigue, muscle weakness and shortness of breath [2,...
Intermittent oxygen deficiency in cancers promotes prolonged inflammation, continuous angiogenesis, and increased drug resistance. Hypoxia-inducible factor-1 (HIF1) has a pivotal role in the regulation of cellular responses to oxygen deficiency. The a-subunit of HIF1 (HIF1a) is degraded in normoxia but stabilized in hypoxia. However, the molecular mechanism that controls oxygen-independent degr...
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