N-acetylcysteine (NAC) is an antioxidant agent which has been shown to benefit patients with fulminant hepatic failure. We have examined its effect in patients with chronic liver disease undergoing orthotopic liver transplantation by giving NAC during operation. In a prospective, randomized, double-blind, placebo-controlled study of 50 patients, NAC appeared to induce mild vasodilatation, impro...

PURPOSE The Crabtree effect is the phenomenon of inhibition of respiration by glycolysis, as a result of elevated glucose levels. It is not certain whether the Crabtree effect occurs in the retina, which has a high glycolytic capacity. In the current study, in vivo photoreceptor oxygen consumption was examined during the normo- and hyperglycemic states in the dark-adapted cat retina to determin...

Introduction: The purpose of this study was to determine Na-Ca exchanger 2, 3 (NCX2, 3) protein level changes during 2, 5, 10, 15 days after induction of normobaric hyperoxia (HO) preconditioning. Materials and Methods: Rats were divided in two experimental groups. The first group was exposed to 95% inspired HO for 4 h/day for 6 consecutive days (HO). The second group acted as control, and was...

Igo-192. rggg.---The surgical technique of isolation of the blood supply of the gracilis muscle of the dog has been developed for analysis of the oxygen consumption during reactive hyperemia. The time course of the blood flow, A-V oxygen difference and the oxygen consumption follow the same pattern. Immediately after the release of the arterial occlusion, there is an increase in all three value...

The photo shows the Isolator which was developed in 1925 by Hugo Gernsback to treat conditions such as attention-deficit hyperactivity disorder. 1 The patient would wear the diving bell-like apparatus. Outside sound was excluded and the eye holes 'focussed' one's attention on the task at hand. The Isolator came with its own oxygen supply to ensure the patient did not suffocate during treatment.

the hybrid molten/solid in2o3 - 30-48 wt.% bi2o3 oxide materials were studied with respect to their transport properties. the conductivities, oxygen ion transport numbers and oxygen permeation fluxes have been measured by using the four-probe dc, volumetric measurements of the faradaic efficiency and gas flow techniques, respectively. we show that the oxygen permeability of the hybrid molten/so...

introduction: oxygen is a drug and physician and nurses should be familiar with the effects and potential risks of oxygen therapy. the current study aimed to assess familiarity of physicians and nurses with various aspects of oxygen therapy. method: in this cross sectional study, the familiarity of physicians and nurses with various aspects of oxygen therapy in a teaching hospital was evaluated...

Kitahori, Kawata, Takamoto et al. described the effectiveness of a novel protocol for retrograde cerebral perfusion that included intermittent pressure augmentation for brain protection in a canine model. Based on their report, we applied this novel technique clinically. Although the duration of circulatory arrest with retrograde cerebral perfusion was long, the patient recovered consciousness ...