Citation: Kovács K, Virányi Z, Kis A, Turcsán B, Hudecz Á, Marmota MT, Koller D, Rónai Z, Gácsi M and Topál J (2018) Dog-Owner Attachment Is Associated With Oxytocin Receptor Gene Polymorphisms in Both Parties. A Comparative Study on Austrian and Hungarian Border Collies. Front. Psychol. 9:435. doi: 10.3389/fpsyg.2018.00435 Dog-Owner Attachment Is Associated With Oxytocin Receptor Gene Polymorp...

s | 39 Abstract Oxytocin has been proposed as a potential treatment approach in drug addiction, but little is known about the effects of oxytocin in translationally relevant models of addiction or the neurobiological substrates of the actions of oxytocin. This presentation highlights the ability of oxytocin to reduce drug taking and drug seeking in a rat model of methamphetamine (meth) addictio...

Introduction The nonapeptides oxytocin and vasopressin belong to an ancient peptide hormone family with representatives in both protastome and deuterostome lineages. The two mammalian hormones themselves probably diverged from a common ancestor at about the time that vertebrates evolved on the earth. There are discrete oxytocin-like and vasopressin-like peptides in teleost fish; only in cyclost...

A number of studies have implicated the neurohypophyseal peptides oxytocin and vasopressin in the central mediation of complex social behaviors, including affiliation, parental care and territorial aggression. Research on a monogamous rodent, the prairie vole (Microtus ochrogaster), suggests that these neuropeptides are also involved in the control of several behaviors associated with monogamy,...

Vasopressin- and oxytocin-related neuropeptides are key regulators of animal physiology, including water balance and reproduction. Although these neuropeptides also modulate social behavior and cognition in mammals, the mechanism for influencing behavioral plasticity and the evolutionary origin of these effects are not well understood. Here, we present a functional vasopressin- and oxytocin-lik...

The rat uterus receives an innervation from the lumbosacral and thoracolumbar segments of the spinal cord. These segments receive descending oxytocinergic projections from the paraventricular nucleus of the hypothalamus. We tested the hypothesis that oxytocin regulates uterine motility through a spinal site of action. Oxytocin was administered in anesthetized female rats either intrathecally at...

Objective: Mesenchymal stem cells (MSCs) are also promising in immunosuppressed patients after organ and tissue transplantation, addition to their current wide range of uses research areas. Sunitinib is a receptor tyrosine kinase with immunosuppressive properties its cytotoxic activity different types known. Our study aimed elucidate the effect oxytocin on sunitinib-treated MSCs.
 Methods:...

In the last several decades, sophisticated experimental techniques have been used to determine the neurobiology of the oxytocin and vasopressin systems in rodents. Using a suite of methodologies, including electrophysiology, site-specific selective pharmacology, receptor autoradiography, in vivo microdialysis, and genetic and optogenetic manipulations, we have gained unprecedented knowledge abo...

Yao Y, Fu L-Y, Zhang X, van den Pol AN. Vasopressin and oxytocin excite MCH neurons, but not other lateral hypothalamic GABA neurons. Am J Physiol Regul Integr Comp Physiol 302: R815–R824, 2012. First published January 18, 2012; doi:10.1152/ajpregu.00452.2011.—Neurons that synthesize melanin-concentrating hormone (MCH) colocalize GABA, regulate energy homeostasis, modulate water intake, and inf...

Gonadal steroid feedback to oxytocin neurons during pregnancy is in part mediated via the neurosteroid allopregnanolone (3alpha-OH-DHP), acting as allosteric modulator of postsynaptic gamma-aminobutyric acid type A (GABA(A)) receptors. We describe here a form of nongenomic progesterone signaling by showing that 3alpha-OH-DHP not only potentiates GABA(A) receptor-channel activity but also preven...