Hypothyroidism is known to be associated with mental retardation, motor dysfunction, memory deficits and hearing impairment. In the present study, the functional integrity of the thalamocortical projections to the primary auditory cortex and association cortex has been assessed by using Auditory Evoked Responses i.e Auditory Brainstem (ABR), Mid Latency Response (MLR) and Slow Vertex Response (...

1. Collateral damage, in military jargon, refers to unintended carnage that is a consequence of waging war. At Vanderbilt biomedical engineers are attacking the problem of “collateral damage” that results from battling disease. Their goal is to make medical procedures free of side effects. New technology-guided therapy, the result of collaborations between biomedical engineers and surgeons, is ...

BACKGROUND Allergic disease can be characterized as manifestations of an exaggerated inflammatory response to environmental allergens triggers. Mite allergen Der-p2 is one of the major allergens of the house dust mite, which contributes to TLR4 expression and function in B cells in allergic patients. However, the precise mechanisms of Der-p2 on B cells remain obscure. METHODOLOGY/PRINCIPAL FI...

The Cox protein from bacteriophage P2 is a small multifunctional DNA-binding protein. It is involved in site-specific recombination leading to P2 prophage excision and functions as a transcriptional repressor of the P2 Pc promoter. Furthermore, it transcriptionally activates the unrelated, defective prophage P4 that depends on phage P2 late gene products for lytic growth. In this article, we ha...

We investigate the unpolarized virtual photon structure functions F 2 x;Q2; P2 and F L x;Q2; P2 in perturbative QCD for the kinematical region 2 P2 Q2, where Q2 ( P2) is the mass squared of the probe (target) photon and is the QCD scale parameter. Using the framework of the operator product expansion supplemented by the renormalization group method, we derive the definite predictions for the mo...

In the late 1980s and early 1990s, most state pollution prevention (P2) efforts focused on the provision of technical assistance, based on the premise that a lack of technical knowledge was the primary impediment to business implementation of P2. It has become increasingly apparent that technical assistance alone is insufficient to motivate systematic change in industry. As a result, state and ...

The regulatory metabolite fructose-2,6-bisphosphate (Fru-2,6P2) has an important function in controlling the intermediary carbon metabolism of leaves. Fru-2,6-P2 controls two cytosolic enzymes involved in the interconversion of fructose-6-phosphate and fructose-1,6-bisphosphate (fructose-1,6-bisphosphatase and pyrophosphate,fructose-6-phosphate 1-phosphotransferase) and thereby controls the par...

During exocytosis, certain phospholipids may act as regulators of secretion. Here, we used several independent approaches to perturb the phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] level in bovine chromaffin cells to investigate how changes of plasmalemmal PI(4,5)P2 affect secretion. Membrane levels of PI(4,5)P2 were estimated by analyzing images of lawns of plasma membranes labeled with ...

The master differential equations in the external square momentum p2 for the master integrals of the two-loop sunrise graph, in n-continuous dimensions and for arbitrary values of the internal masses, are derived. The equations are then used for working out the values at p2 = 0 and the expansions in p2 at p2 = 0, in (n− 4) at n → 4 limit and in 1/p2 for large values of p2. ——————————PACS 11.10....

Abstract In the summer of 2020, South Korea experienced record-breaking rainfall due to 15 consecutive heavy events (HREs) from mid-June early September. Among them, 11 HREs occurred in late June mid-August with distinct synoptic characteristics depending on occurrence period. All 29 27 July (P1) were triggered by extratropical cyclones, while those 28 August (P2) mainly along monsoon rainband....