Key Points  Loss or injury of pad tissue, despite an otherwise normal limb, can result in complete loss of limb function, so preserving pad function is critical for most small animals.  Skin around the pad may in some cases be able to adapt to function similar to pad tissue but it is generally accepted that adjacent skin is not a suitable replacement for lost pad tissue, particularly in activ...

OBJECTIVES The purpose of this study was to determine the association of family history of peripheral artery disease (PAD) with PAD prevalence and severity. BACKGROUND PAD is a significant public health problem. Shared genetic and environmental factors may play an important role in the development of PAD. However, family history of PAD has not been investigated adequately. METHODS The San D...

Lower extremity peripheral arterial disease (PAD) is prevalent in the Medicare population and is associated with high rates of myocardial infarction, stroke, amputation, and death. Nevertheless, national health expenditures for PAD are not known. We hypothesized that PAD-related costs are high, increase with age, and that treatment rates would be less than known PAD prevalence. The objective wa...