In 2020, 146,063 deaths due to pancreatic cancer are estimated to occur in Europe and the United States combined. To identify common susceptibility alleles, we performed the largest pancreatic cancer GWAS to date, including 9040 patients and 12,496 controls of European ancestry from the Pancreatic Cancer Cohort Consortium (PanScan) and the Pancreatic Cancer Case-Control Consortium (PanC4). Here...

Classical Fault Tree Analysis (FTA) can determine the effects of combinations of failure events on a system but cannot capture the potentially critical significance of the temporal ordering of events. In this paper, we propose a temporal extension based on the use of Priority-AND gates to allow relative temporal ordering and temporal analysis in FTA. The classical notion of minimal cut-sets is ...

We studied the effects of soil matric potential and salinity on the water use (WU), water use efficiency (WUE) and yield response factor (Ky), for wheat (Triticum aestivum cv. Mahdavi) and bean (Phaseoulus vulgaris cv. COS16) in sandy loam and clay loam soils under greenhouse conditions. Results showed that aeration porosity is the predominant factor controlling WU, WUE, Ky and shoot biomass (B...

Pandora moths (Coloradia pandora subsp. davisi Barnes and Benjamin) have been observed to reach epidemic populations on the Kaibab Plateau, resulting in relatively small, localized defoliation events of ponderosa (Pinus Lawson). We reconstructed historical moth outbreak regime using tree rings forest health records explore how exogenous factors, climate, fire, are related dynamics close driest ...