OBJECTIVE This study examines the relationship between parental alcohol use disorders (AUDs) and child violent and nonviolent delinquency. It also explores the mediating effects of executive functioning and chronic family stress on the parental AUD/child delinquency relationship. METHOD Participants were 816 families with children (414 boys and 402 girls) born between 1981 and 1984 at Mater M...

In most eukaryotes, mitochondria are inherited maternally. The autophagy process is critical for paternal mitochondrial elimination (PME) in Caenorhabditis elegans, but how paternal mitochondria, but not maternal mitochondria, are selectively targeted for degradation is poorly understood. Here we report that mitochondrial dynamics have a profound effect on PME. A defect in fission of paternal m...

Within the last few decades our understanding of the importance of non-cognitive skills for socioeconomic success has grown along with our knowledge of the deleterious impacts of paternal incarceration for child wellbeing. Given the importance of early skills and that elementary-aged children constitute the majority of children with incarcerated parents, understanding the connection between pat...

background: androgen insensitivity syndrome (ais) or testicular feminization is a partial or complete inability of cell response to androgen. the cause is enzymatic defect in synthesis of testosterone, resulting sexually immature phenotypically female, with primary amenorrhea. there are three categories of ais, complete, partial and mild, depending on the degree of external genital masculinizat...

BACKGROUND Maternal smoking during pregnancy has been reported to negatively impact sperm counts of the sons. Sufficient data on the effect of paternal smoking is lacking. OBJECTIVES We wished to elucidate the impact of maternal and paternal smoking during pregnancy and current own smoking on reproductive function of the male offspring. METHODS Semen parameters including sperm DNA integrity...

BACKGROUND The role of advanced maternal age as a risk factor for congenital malformations in offspring is known. However, the influence of paternal age is not clear. AIM To evaluate the association between advanced paternal age and the risk for congenital malformations. PATIENTS AND METHODS Analysis of maternal and paternal age of cases (malformed newborns) and controls from ECLAMC Databas...

BACKGROUND Research on predictors of birth outcomes tends to focus on maternal characteristics. Less is known about the role of paternal factors. Missing paternal data on administrative records may be a marker for risk of adverse birth outcomes. DATA AND METHODS Analyses were performed on a cohort of births that occurred from May 16, 2004 through May 15, 2006, which was created by linking bir...

Many flowering plants are polyploid, but crosses between individuals of different ploidies produce seeds that develop abnormally and usually abort. Often, seeds from interploidy crosses develop differently depending on whether the mother or father contributes more chromosome sets, suggesting that maternal and paternal genomes are not functionally equivalent. Here we present the first cytologica...

OBJECTIVE Based on emerging preclinical findings suggesting that paternal smoking at conception may be a risk for ADHD in the offspring, we investigated whether a similar effect can be observed in humans. METHOD We analyzed data from an opportunistic dataset of girl probands with ( N = 140) and without ( N = 122) ADHD with available information on paternal smoking at conception. Data were ana...