OBJECTIVE Recent advances in different MRI sequences have enabled direct visualization and targeting of the Globus pallidus internus (GPi) for DBS surgery. Modified Driven Equilibrium Fourier Transform (MDEFT) MRI sequences provide high spatial resolution and an excellent contrast of the basal ganglia with low distortion. In this study, we investigate if MDEFT sequences yield accurate and relia...

The objective of this study was to investigate whether eye-hand coupling was preserved or not in PD. We studied predictive saccade performance during hand pointing in six Parkinson's disease (PD) patients with asymmetrical motor signs compared to nine age-matched healthy subjects. The motor responses (saccades and hand pointing) were elicited under open loop conditions (without vision of the ha...

Partial discharge (PD) localization is critical to ensure the safe operation of power equipment. In this paper, an optimization scheme developed for PD positioning external insulation The based on eight-element cross sensor array receive ultrasonic signal generated by PD, and uses highly accurate 2-D multiple classification (2-D MUSIC) algorithm locate signal. Simulated adopted test scheme, res...

BACKGROUND Whether diabetes increases the risk of Parkinson's disease (PD) is still inconclusive. The objective of this updated meta-analysis is to synthesize evidence from case-control studies that evaluated the association between diabetes and the risk of PD. METHODS Seven databases were searched to identify case-control studies that evaluated the association between diabetes and PD. The me...

Objectives: In the early stages, most Parkinson’s patients display some degrees of voice and speech disorders. Speech disorders can negatively affect social interactions and human life, thus treatment plans for the disorders in the early stages might be further beneficial than the late stages. Therefore, we aimed to investigate on the effect of an intervention on Persian patients with early mil...

In a polar map display, the LAD originates from an area corresponding to 11 o’clock, and the relationship between localization of the culprit lesion and diagonal arteries can be inferred by the extent of decreased perfusion extending from 12 o’clock towards 1 o’clock. The location of a lesion in the LCX main trunk can be inferred by whether decreased perfusion is observed at any level within 2〜...

A new peridynamic (PD) model for crevice corrosion damage is introduced and cross-validated with experimental results from the literature. Electrochemical mechanisms are reduced to a simple metal-ion concentration-dependent rate. Computations over domains extreme aspect ratios like those seen in crevices efficiently performed by modifying PD formulation accommodate arbitrary-shape horizons. The...

OBJECTIVE To assess whether Parkinson disease (PD) genes are somatically mutated in cutaneous melanoma (CM) tissue, because CM occurs in patients with PD at higher rates than in the general population and PD is more common than expected in CM cohorts. METHODS We cross-referenced somatic mutations in metastatic CM detected by whole-exome sequencing with the 15 known PD (PARK) genes. We compute...

The subthalamic nucleus (STN) plays a crucial role in the surgical treatment of Parkinson's disease (PD). Studies investigating optimal protocols for STN visualization using state of the art magnetic resonance imaging (MRI) techniques have shown that susceptibility weighted images, which display the magnetic susceptibility distribution, yield better results than T1-weighted, T2-weighted, and T2...

Partial discharge within the dielectric of HV solid dielectric power cable greatly shortens the cable life. It is desirable to detect and locate the PD in the cable before breakdown occurs. Understanding the phenomena of propagation of the PD pulse in a power cable is fundamental to the detection and location of PDs. In this paper a power cable model represented by a coaxial transmission lossle...