A simple, rapid and precise method was developed for the quantitative estimation of prasugrel hydrochloride in pharmaceutical dosage form. A chromatographic separation of prasugrel and its degradants was achieved with Zorbax XDB C(8), 150 × 4.6 mm, 3.5μm analytical column using aqueous solution of 0.05 M ammonium acetate pH 4.5 with acetic acid-acetonitrile (40:60 v/v). The instrumental setting...

Horseradish peroxidase (HRP) and thionine (TN) were co-adsorbed onto a porous carbon felt (CF), and the resulting HRP and TN-adsorbed CF (HRP-TN-CF) was successfully used as a working electrode unit of a novel bioelectrocatalytic flow detector for a highly sensitive amperometric determination of hydrogen peroxide (H(2)O(2)). Co-adsorbed TN was essential to enhance the cathodic peak current of H...

We derive an approximate intrapixel sensitivity variation (IPSV) of the IR-1 detector of WFC3 from ground-test imagery. The purpose was to assess whether additional testing of this sort should be performed in Thermal Vacuum 3 (TV3) testing, scheduled to commence in February 2008. Whereas NICMOS exhibits IPSV as large as 40%, peak to valley, in the photometry of stars observed in J band with the...

The e + e ? collider VEPP-2M at Novosibirsk is the only machine covering the energy range 360-1400 MeV. The peak luminosity is 5: 10 30 cm ?2 s ?1 for the resonance region. Two modern detectors-the general purpose magnetic detector CMD-2 and Spherical Neutral Detector (SND) are taking data at the VEPP-2M collider. The integrated luminosity about 10 pb ?1 has been collected by both detectors. La...

The Monte Carlo method is increasingly applied for simulation of germanium detectors. It can be successfully used for the evaluation of full energy peak efficiency or of the efficiency corrections due to self-attenuation, coincidence summing and geometry effects. Usually the simulation task is to evaluate the energy deposited in the sensitive volume of the detector, assuming that the detector s...

A filterbank-based algorithm for time-varying spectral analysis is proposed. The algorithm, which is an enhanced realization of the conventional spectrogram, consists of hundreds or thousands of highly overlapping wideband filter/detector stages, followed by a peak detector that probes the filter/detector outputs at very short time intervals. Analysis with synthetic modulated signals illustrate...

Among the secondary detection effects in gamma-ray spectroscopy with HPGe detectors that reduce the peak area and must be properly taken into account in accurate measurements, the less well known is counting loss by beta and gamma-ray sum coincidence. The fraction of lost counts was estimated assuming that a photon detection event can sum either with the coincident beta-ray or its bremsstrahlun...

A Monte Carlo computer program has been used to calculate characteristics of the response of fully depleted silicon and germanium radiation detectors to monoenergetic gamma rays. Data for total absorption probability, intrinsic efficiency, escape peak efficiency and pulse height spectra are presented as functions of detector thickness and photon energy. Other parameters of interest in analysing...

BACKGROUND Detection of characteristic waves, such as QRS complex, P wave and T wave, is one of the essential tasks in the cardiovascular arrhythmia recognition from Electrocardiogram (ECG). METHODS A multiscale morphological derivative (MMD) transform-based singularity detector, is developed for the detection of fiducial points in ECG signal, where these points are related to the characteris...

The first break our watermarking system (BOWS) contest challenged researchers to remove the watermark from three given images. Participants could submit altered versions of the images to an online detector. For a successful attack, the watermark had to be unreadable to this detector with a quality above 30 dB peak signal-to-noise ratio. We implemented our experiments in R, a language for statis...