background peptic ulcer disease is a multifactorial health problem affecting almost all populations worldwide. large scale population-based studies are crucial to understanding its scope and specifications in various nations. we aimed to explore environmental risk factors of peptic ulcer disease in the first population based study in ardabil, northwest iran. methods this study was a part of a l...

objective: it has been noted that the presence of helicobacter pylori (h. pylori) in the oral cavity may affect the outcome of eradication therapy. this condition is associated with the recurrence of gastric infection. the optimum secretion of saliva promotes oral health consequently influencing h. pylori eradication. the purpose of this study was to investigate the relation between salivary se...

background: cd1d presents glycolipid antigens to invariant natural killer t (inkt) cells. the role of cd1d in the development of peptic ulcer and gastric cancer has not been revealed, yet. objective: to clarify the expression of alternatively spliced variants of cd1d in peptic ulcer and gastric cancer. methods: patients with dyspepsia were selected and divided into three groups of non-ulcer dys...

background: helicobacter pylori (h.p) and non steroidal anti inflammatory drugs (nsaid) are the most common cause of peptic ulcer disease (pud). this study was designed to identify endoscopic, clinical and demographic features of patients with h.p positive in comparison with nsaid related pud.methods: from december 2004 to march 2008, 5885 patients underwent upper gi tract endoscopy in a large ...

purpose: to compare the prevalence of glaucoma among peptic ulcer patients with or without helicobacter pylori infection. methods: among 352 patients with an indication of gasterointestinal endoscopy for peptic problems, 120 patients in 18-88 years of age were included for evaluation of glaucoma. according to the results of histopathologic and urease test, they were divided into two groups: hel...

Symptoms of 50 patients with the irritable bowel syndrome were compared with those of 49 with endoscopically proven peptic ulcer disease and 49 with radiologically or endoscopically proven inflammatory bowel disease using a questionnaire which was administered after the diagnosis was made. Symptoms of bowel dysfunction including pain related to bowel movements were more likely to occur in the i...

Symptoms of 50 patients with the irritable bowel syndrome were compared with those of 49 with endoscopically proven peptic ulcer disease and 49 with radiologically or endoscopically proven inflammatory bowel disease using a questionnaire which was administered after the diagnosis was made. Symptoms of bowel dysfunction including pain related to bowel movements were more likely to occur in the i...

Background—Virulence factors of Helicobacter pylori are associated with peptic ulcer disease and may be also associated with the eYcacy of treatment. Aims—To determine the relation between the vacA and the cagA status of H pylori, clinical disease, and treatment outcome. Patients—121 patients with H pylori infection and peptic ulcer disease or functional dyspepsia were treated by quadruple anti...

Interleukin 12 (IL-12) is a proinflammatory cytokine composed by two chains, p40 and p35, that plays a key role in the promotion of a Th1 immune response in the gastrointestinal mucosa. An enhanced expression of IL-12 mRNA in gastric mucosa has been reported in individuals infected by Helicobacter pylori. The aim of our study was to assess whether a functional polymorphism located at position 1...