OBJECTIVES To show important aspects of gastroduodenal peptic ulcer and of Helicobacter pylori infection in children and adolescents. SOURCES Technical textbooks and MEDLINE and LILACS databases including publications between 1966 and 2006. SUMMARY OF THE FINDINGS The etiology of peptic ulcer in children and adolescents may be primary, associated with H. pylori infection, or secondary, in w...

Since acceptance of the association between Helicobacter pylori and peptic ulcer disease, eradication of H. pylori has become the standard of care in the treatment of peptic ulcer disease. Unfortunately, eradication therapy is no easy task, especially when one is faced with a myriad of drug combinations with varying degrees of efficacy and tolerability. The following is a review of the literatu...

Identification of the pathogenic role of H. pylori in fection has revolutionized the approach toward chronic gastritis, peptic ulcer disease, gastric MALT (mucosa associated lymphoid tissue) lymphoma and gastric can cer. These diseases often result from infection of H. pylori, the accompanying host inflammatory response and the interaction with environmental factors. Eradi cation treatment agai...

A 37 year old male with a history of peptic ulcer disease presented to the emergency room with nausea and vomiting. He reported two recent episodes of syncope, but denied other associated symptoms including palpitations, hematemesis, melena, chest pain, or dyspnea. He reported recent use of marijuana, but denied use of cocaine or methamphetamines. The patient reported similar symptoms in 2006 w...

BACKGROUND Peptic ulcer etiology has been changing because of H. pylori decline. OBJECTIVES To estimate peptic ulcer prevalence in 10 years-interval and compare the association with H. pylori and use of non-steroidal anti-inflammatory drugs. Methods Records assessment in two periods: A (1997-2000) and B (2007-2010), searching for peptic ulcer, H. pylori infection and non-steroidal anti-inflam...

In 1897 Felix Hoffman, a 29-year-old scientist working for the Bayer Company patented a chemical procedure that enabled the acetylation of salicylic acid with the enough purity to be used commercially (Wallace, 1997). The new product was evaluated by Dreser Heinrich, head of marketing at Bayer, who despite some initial misgivings gave his approval for marketing acetylsalicylic acid under the na...

AIM To investigate the long-term prognosis in peptic ulcer patients continuing taking antithrombotics after ulcer bleeding, and to determine the risk factors that influence the prognosis. METHODS All clinical data of peptic ulcer patients treated from January 1, 2009 to January 1, 2014 were retrospectively collected and analyzed. Patients were divided into either a continuing group to continu...

INTRODUCTION: Ulcer is a common disorder of the gastrointestinal system, which causes much discomfort to patients, disrupting their daily routines and causes mental agony. Peptic ulcer is defined as a break off in the continuity of the mucosa of stomach or duodenum as a consequence of some medications like nonsteroidal anti-inflammatory drugs (NSAIDS), gastric acids and pepsin finally causes le...

BACKGROUND/AIMS Data concerning peptic and infectious ulcers in children are limited. The aim of the study was to investigate the prevalence, presenting symptoms and significance of symptomatology in ulcer diagnosis in the pediatric age group. MATERIALS AND METHODS Between January 2000 and 2009, upper gastrointestinal endoscopy charts were examined retrospectively. All children in whom a diag...

The association ofHelicobacter pyloriwith peptic ulcer disease and gastric cancer was first proposed by Warren and Marshall in 1983 (Warren and Marshall, 1983). In February 1994, the National Institutes of Health Consensus Development Conference concluded thatH. pylori infection is themajor cause of peptic ulcer disease, and all patients with confirmed peptic ulcer disease associatedwithH. pylo...