effects of drought stress and chemical treatments was studied on growth and developmental traits of four barley cultivars using a split- split plot design (rcbd) in agricultural research farm, kerman university. main plots consisted of irrigation (control and drought stress after flowering), sub-plots consisted of four barley cultivars ( ʻnosratʼ, ʻafsalʼ, ʻyousofʼ and ʻuh12 lineʼ) and sub-sub ...

AIM To evaluate the prognostic significance of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and prognostic nutritional index (PNI) and other clinicopathological factors in patients undergoing curative resection of colon cancer. METHODS 183 patients with histologically proven colorectal cancer who had undergone potentially curati...

BACKGROUND AND OBJECTIVES Preoperative systemic inflammatory response and nutritional status play important roles in the tumorigenesis, progression, and prognosis of gastric cancer (GC). This research is designed to investigate the prognostic value of the biomarkers including the neutrophil to lymphocyte ratio (NLR), derived neutrophil to lymphocyte ratio (dNLR), monocyte to lymphocyte ratio (M...

Glutaraldehyde fixed patch grafts of bovine pericardium were implanted in myocardial windows in young (3-4 months old) sheep. The samples were retrieved after one to three weeks for study with scanning electron microscopy (SEM) and energy dispersive x-ray microanalysis (EDX). A layer of porous material (pseudoneointima, PNI), consisting mostly of a dense mesh of fibers interspersed with blood c...

Atrial fibrillation ablation has emerged as an effective tool in the management of symptomatic atrial fibrillation. Currently, the electrophysiologists are striving to maximize the success while minimizing complications. Phrenic nerve injury (PNI) is one of the concerning complications, especially in cases of cryoballoon ablation. Due to anatomical proximity to atrial tissue, phrenic nerve is p...

The ability of cancer cells to invade along nerves is associated with aggressive disease and diminished patient survival rates. Perineural invasion (PNI) may be mediated by nerve secretion of glial cell line-derived neurotrophic factor (GDNF) attracting cancer cell migration through activation of cell surface Ret proto-oncogene (RET) receptors. GDNF family receptor (GFR)α1 acts as coreceptor wi...

Phrenic nerve injury (PNI) is a rare complication of catheter ablation therapy, most commonly observed in cryoablation of the right side pulmonary veins. We present a case of PNI after radiofrequency catheter ablation that developed acute dyspnea 24 hours after the intervention. Dyspnea is the main symptom of PNI, so the diagnosis should always be suspected if it appears after any type of cathe...

Perineural invasion (PNI) is an indicator of poor survival in multiple cancers. Unfortunately, there is no targeted treatment for PNI since the molecular mechanisms are largely unknown. PNI is an active process, suggesting that cancer cells communicate with nerves. However, nerve-tumour crosstalk is understudied due to the lack of in vivo models to investigate the mechanisms. Here we developed ...