Hepatocellular carcinoma (HCC) remains a major public health problem. Transarterial chemoembolization (TACE) is recognized as the standard of care for patients with unresectable, asymptomatic, noninvasive and multinodular HCC. This procedure is based on percutaneous administration of a cytotoxic drug emulsified with Lipiodol followed by embolization of the tumour-feeding arteries. The standard ...

BACKGROUND Percutaneous aortic valve implantation by an antegrade transvenous approach has been described but is problematic. Retrograde prosthetic aortic valve implantation via the femoral artery has potential advantages. Percutaneous prosthetic aortic valve implantation via the femoral arterial approach is described and the initial experience reported. METHODS AND RESULTS The valve prosthes...

Purpose & background Despite recent advances in resuscitation medicine, survival rates to discharge following out-of-hospital cardiac arrest (OHCA) remain poor. Recent data support the implementation of early critical care interventions including therapeutic hypothermia (TH) and immediate percutaneous coronary intervention (PCI). We describe a pre-hospital service where early delivery of critic...

Implantation of drug eluting stents following percutaneous transluminal angioplasty has revealed a well established technique for treating occlusions caused by the atherosclerotic plaque. However, due to the risk of vascular re-occlusion, other alternative therapeutic strategies of drug delivery are currently being investigated. Polymeric endoluminal pave stenting is an emerging technology for ...

Percutaneous coronary intervention (PCI) in an anomalous right coronary artery arising from the left sinus of valsalva can be technically challenging because of difficulty in selectively cannulating the vessel. We present two cases of successful stent implantation in an anomalous right coronary artery arising from the left sinus of valsalva. In both cases, we used an oversized 6 Fr Judkins left...

In image-guided brachytherapy (IGBT), accurate percutaneous intervention of needle and precise placement radiation sources are challenge tasks. In traditional prostate brachytherapy, needles are introduced through fixed, parallel holes of a template where the maneuverability of the needle is extremely limited. The accuracy and consistency of needle placement and seed delivery is subject to vari...

A topical preparation containing aceclofenac was developed using an o/w microemulsion system. Isopropyl myristate was chosen as the oil phase as it showed a good solubilising capacity. Pseudo-ternary phase diagrams were used to obtain the concentration ranges of the oil, surfactant (Labrasol) and co-surfactant (plurol oleique) for microemulsion formation. Five different formulations were formul...

background: significant elevation of cardiac biomarkers after percutaneous coronary intervention (pci) is associated with increased mortality. however, clinical importance of lesser degrees of cardiac enzyme elevation has not been well understood. multiple factors might have an etiologic role, and the incidence of myonecrosis has not changed dramatically despite pharmacological and technologica...

peripherally inserted venous ports fracture with embolization in patients who received chemotherapy is a serious and rare complication,and few cases have been reported in children. we report a successful endovascular technique using a snare for retrieving broken peripherally inserted venous ports in a child for chemotherapy. catheter fragments may cause complications such as cardiac perforation...

BACKGROUND Manipulating gene expression in the failing heart has therapeutic promise, but until now efficient and homogeneous cardiac gene delivery has required an open-chest approach. This study examines the hypothesis that vector delivery promoted by echo contrast microbubbles will be maximized by injection of the vectors into the aortic root with brief balloon occlusion above the sinuses, wh...