Abstract Introduction Acute hypersomnia is a rare presentation of bilateral paramedian thalamic strokes (PTS). The typical symptoms vertical gaze palsy, memory impairment, and even coma, do not include acute hypersomnia. Hypersomnia can be normal in appropriate settings. However, from wake state abnormal should alert observers to potential stroke, making timely intervention consequential patien...

Abstract Introduction Hypersomnia sleep disorders are characterized by overwhelming daytime sleepiness. Treatment options include sodium oxybate the salt of γ-hydroxybutyric acid (GHB). Oxybate, an endogenous metabolite GABA, acts through GABAB noradrenergic and dopaminergic neurons, as well at thalamocortical neurons. < 1% may experience suicidal ideations or psychosis. Report case(s) A...

BACKGROUND Sleep disturbance is very common following traumatic brain injury (TBI), which may initiate or exacerbate a variety of co-morbidities and negatively impact rehabilitative treatments. To date, there are paradoxical reports regarding the associations between inherent characteristics of TBI and sleep disturbance in TBI population. The current study was designed to explore the relationsh...

BACKGROUND AND PURPOSE Hypersomnia, sleep-disordered breathing and narcoleptic traits such as rapid eye movement (REM) sleep onset periods (SOREMPs) have been reported in Prader-Willi syndrome (PWS). In a group of young adult patients with genetically confirmed PWS we evaluated sleep and breathing polysomnographically, including cycling alternating pattern (CAP), and we analyzed the potential i...

Obstructive sleep apnea (OSA) is an extremely common public health problem manifested by sleep-disordered breathing, daytime hypersomnia and poor sleep quality, adverse neurocognitive sequelae, and hypoxia. OSA occurs in about two to four percent of the general population, or an estimated 18 million Americans. Co-morbid OSA is even more frequent in neurological patients, affecting at least one-...

Abstract Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). ADHD also often express sleep problems including EDS. Thus, patients and idiopathic hypersomnia narcolepsy may share drowsiness as common features. However, it is not known whether EDS have...