PURPOSE To evaluate the acute effects of laser in situ keratomileusis (LASIK) upon the synthesis of proteoglycans (PGs) and collagen fibril organization in human corneal explants. METHODS Human corneas that had been rejected for transplants were obtained at Banco de Olhos of Hospital São Paulo. For each eye pair, one cornea was submitted to refractive surgery, and the other was used as its ma...

A 52-year-old man with burn injuries and prolonged intubation developed PGS with hoarseness, dyspnea, and bilateral vocal cord immobility. On CT, a calcified interarytenoid scar band was identified, corresponding to an interarytenoid scar on laryngoscopy. Endoscopic laser lysis of the calcified scar band relieved the symptoms. We present laryngoscopic and CT findings of PGS with interarytenoid ...

Biodegradable elastomeric materials are gaining extensive attention in the field of soft tissue engineering. Poly (glycerol sebacate) (PGS) is a novel biocompatible elastomer in this scope. However this polymer has poor mechanical properties especially when the molar ratio of glycerol is higher than sebacic acid. Calcium Titanate (CaTiO3) is a biocompatible ceramic with some degr...

Electroconductive scaffolds can be a promising approach to repair conductive tissues when natural healing fails. Recently, nerve tissue engineering constructs have been widely investigated due the challenges in creating structure with optimized physiochemical and mechanical properties close native tissue. The goal of current study was fabricate graphene-containing polycaprolactone/gelatin/polyp...

Recently, pocket green spaces (PGS), i.e., small spaces, have attracted growing attention for their various ecological and social services. As a crucial part of urban in high-density areas, PGS facilitates recreation relaxation neighborhoods thus improves the livability cities at local scale. However, whether how cools heat island effect is still unclear. This research was performed highly deve...

Although the clinical efficacy of prostaglandins (PGs), especially on gastric mucosal injuries induced by nonsteroidal antiinflammatory drugs, is widely appreciated, their mechanism of action, apart from acid suppression, is quite unclear. In this study, we have established a primary culture system of human gastric fibroblasts and clearly demonstrated that PGs strongly induce the expression of ...