The immuno-pharmacological properties of ethanolic extract of Nyctanthes arbor-tristis Linn. (NA) have been investigated. After administration of Nyctanthes arbor-tristis in doses of 0.25 and 0.5 g/kg body weight (BW) a significant increase in phagocytic index, leukocyte count and spleenic antibody secreting cells were noticed. Stimulation of humoral immune response was further observed with he...

Cancer is one of the leading causes of death worldwide. Many treatments have been developed so far, although effective, suffer from severe side effects due to low selectivity. Nanoparticles can improve the therapeutic index of their delivered drugs by specifically transporting them to tumors. However, their exogenous nature usually leads to fast clearance by mononuclear phagocytic system. Recen...

BACKGROUND Infections by a variety of pathogens are a significant cause of morbidity and mortality during perinatal period. The susceptibility of neonates to bacterial infections has been attributed to immaturity of innate immunity. It is considered that one of the impaired mechanisms is the phagocytic function of neutrophils and monocytes. The purpose of the present study was to investigate th...

Phagocytosis of bacteria by innate immune cells is a primary method of bacterial clearance during infection. However, the mechanisms by which the host cell recognizes bacteria and consequentially initiates phagocytosis are largely unclear. Previous studies of the bacterium Pseudomonas aeruginosa have indicated that bacterial flagella and flagellar motility play an important role in colonization...

Phagocytosis is a phylogenetically ancient process triggered by particulate ligands, such as bacteria, fungi and environmental particles. The spectrum of phagocytically competent cell types and receptors is diverse, but many of the basic processes of cytoskeletal rearrangement and membrane trafficking that accompany phagocytosis are conserved. Insights from studies of lower eukaryotes, such as ...

The determinants of a substantial portion of bond credit spreads remain puzzled in literature. Through investigating corporate bond credit spreads from year 2000 to 2005, we find that corporate internal liquidity still significantly impacts on corporate bond credit spreads when controlling other well-known variables stated in literature. Additionally, we also find that there is a systematic int...

The leaves of Butea monosperma (Lamk) Taub (Fabaceae) have been traditionally used as tonic. Ethanolic extract of Butea monosperma contains flavonoids, glucosides, butin, butrin, isobutrin, palastrin. The present study was undertaken to evaluate the immunomodulatory activity of Butea monosperma leaves. Ethanolic extract of Butea monosperma leaves was administered at dose of 100, 200 and 400 mg/...

Wandering cells migrate from cultures of human lymph nodes after 2 or 3 hours incubation; they are actively ameboid and phagocytic. Endothelial cells appear in the plasma clot after 24 to 48 hours incubation. They are relatively inactive and less phagocytic. Fibroblasts are seen after 48 hours incubation. They are inactive and not phagocytic. The probable origin of wandering cells from endothel...

PURPOSE The purpose of this study was to compare the in-vitro effects of a European-based formocresol formulation that incorporates eugenol with formocresol alone on the adhesion of macrophages to plastic surfaces. METHODS Macrophages were obtained from Wistar rats. The adherence capacity of macrophages to a plastic surface was determined. Assays were carried out in Eppendorf tubes incubated ...