Several cases of Candida bloodstream infections were documented from June to October 2004 at a tertiary care center in Bogotá, Colombia. Since no cases of candidemia had occurred during the preceding four months, an outbreak was declared. As a result, a microbiological study, a revision of infection control practices and a case-control study were performed. In all, 18 cases of candidemia were a...

BACKGROUND It is globally agreed that a well-designed health system deliver timely and convenient access to health services for all patients. Many interventions aiming to reduce waiting times have been implemented in Chinese public tertiary hospitals to improve patients' satisfaction. However, few were well-documented, and the effects were rarely measured with robust methods. METHODS We condu...

The development of new approaches to the construction of fluorine-containing target molecules is important for a variety of scientific disciplines, including medicinal chemistry. In this Article, we describe a method for the catalytic enantioselective synthesis of tertiary alkyl fluorides through Negishi reactions of racemic α-halo-α-fluoroketones, which represents the first catalytic asymmetri...

OBJECTIVES Lincoln Community Health Center participated in a Health Resources and Services Administration-sponsored Patient Safety and Clinical Pharmacy Services Collaborative aimed at facilitating integration of pharmacy services proven to enhance patient safety into care provided to a high-risk, ambulatory population. METHODS The Collaborative used the Plan-Do-Study-Act (PDSA) cycle of lear...

BACKGROUND Pharmaceutical representatives often give sample medications to physicians for distribution to patients. In chronic conditions such as hypertension, this practice can contribute to unnecessary medication changes, gaps in treatment, and inferior control of disease. The objective of the current study was to explore associations between use of free sample medicine, hypertension, and sou...

INTRODUCTION Food-dependent exercise-induced anaphylaxis (FDEIA) is an uncommon and under-recognised syndrome that clinicians may not consider in a patient presenting with anaphylaxis. CLINICAL PICTURE We describe here 5 patients aged 9 to 20 years old who presented at a local tertiary hospital over a 2-year period from August 2006 to July 2008. All presented with urticaria, 4 were hypotensiv...

OBJECTIVE To investigate systematically participation in audit of NHS hospital pharmacists in the United Kingdom. DESIGN Questionnaire census survey. SETTING All NHS hospital pharmacies in the UK providing clinical pharmacy services. SUBJECTS 462 hospital pharmacies. MAIN MEASURES Extent and nature of participation in medical, clinical, and pharmacy audits according to hospital manageme...

CONTEXT Junior doctors are reported to make most of the prescribing errors in the hospital setting. AIMS The aim of the following study is to determine the knowledge intern doctors have about prescribing errors and circumstances contributing to making them. SETTINGS AND DESIGN A structured questionnaire was distributed to intern doctors in National Hospital Abuja Nigeria. SUBJECTS AND MET...

Background Initiation of specific antimalarial treatment within 24 hrs of fever onset at home and before presentation to the hospital is one of the strategies to reduce mortality from malaria in sub-Saharan Africa. In order to determine whether this strategy is being implemented we describe the use and factors associated with the use of pre-hospital medications among children admitted with mala...