The considerable importance of ?-arylated carbonyl compounds, which are widely used in the pharmaceutical industry, has prompted efficient synthetic strategies for their preparation.

indole is a nitrogen-containing heterocycle. it is a very important motif in agriculture and pharmacy. many compounds containing indole moiety has been isolated form nature. it is also an important part in natural alkaloids. tryptophan is an amino acid which posses indole. 3-sustituted indoles are the main group of its derivatives. because the wide-spread application of 3-substituted indolic co...

background & aim: identification, characterization and detection of medicinal plants chemical composition are very important for phytochemical scientific source. sumac is one of the medicinal plants in the world that uses for industrial and pharmacological application. in this study, chemical composition of rhus coriaria has been investigated. experimental: chemical composition of the matu...

Ten molecularly diverse compounds, selected on the basis of the standard free energy of complexation with β-cyclodextrin, have been used as training set of molecular docking experiments. After the conformational search of each compound the Molecular Interaction Evaluation (MOLINE) program has been adopted to generate the inclusion geometries. The recognition process has been thermodynamically e...

Paper reports the results of landfill leachate treatment with membrane bioreactor, nanofiltration and ozonation. Investigated leachate encompasses a number of specific compounds of pharmaceutical origin, including a suite of by-products deriving from the production of vitamin C and propyphenazone. Low biodegradability was observed in MBR (16%) for propyphenazone, while the removal of intermedia...

Marine organisms have been recognized as rich sources of bioactive compounds with valuable nutraceutical and pharmaceutical potentials. Recently, marine bioactive peptides have gained much attention because of their numerous health beneficial effects. Notably, these peptides exhibit various biological activities such as antioxidant, anti-hypertensive, anti-human immunodeficiency virus, anti-pro...

maceutical industry for production of fine drug particles with narrow size distribution, separation of active ingredients and preparation of microemulsions and sustained drug delivery systems. Supercritical carbon dioxide (SC-CO2) is a very popular fluid for pharmaceutical applications, as it is nontoxic, non-flammable and of low cost. Furthermore, because of its low critical temperature and pr...

Indolo[3,2-c]quinolines are pharmacologically attractive class of heterocyclic compounds. The method of their synthesis, based on transformation of furfural, which is a large-scale product of treatment of biomass including agricultural and forestry wastes, has been developed. This method was utilized for the total synthesis of antimalarial alkaloid isocryptolepine and its derivatives.