to improve drug selectivity toward target cells, one interesting approach for drug delivery is to use polymer nanoparticles. a two-layered oniom becke3- lyp: uff calculation was carried out to study the structural and thermodynamic properties of the interaction between acetamide derivatives and the pca-peg-pca copolymers. the interaction enthalpies and the gibbs free energies between acetamide ...

titanium dioxide (tio2)nanoparticles have been frequently employed in the environmental treatment and purification purposes as a cheap and highly efficient photocatalyst. a photocatalyst can facilitate the breakdown and removal of a variety of environmental pollutants at room temperature. tio2 photocatalyst is the best candidatebecause of its strong oxidized ability, non-toxicity and longtherma...

introduction:yasthenia gravis is an autoimmune disorder resulting from a decreased number of active acetylcholine receptors at the neuromuscular junction. thymectomy is one of its current treatments. due to sensitivity of myasthenic patients to non-depolarizing muscle relaxants and also the interaction of this medication with anti-cholinestrase drugs, determining the dosage of non-depolarizing ...

an artificial neural network (ann) model is developed for the analysis, simulation, and prediction of the austenite reversion in the thermo-mechanical treatment of 304l austenitic stainless steel. the results of the ann model are in good agreement with the experimental data. the model is used to predict an appropriate annealing condition for austenite reversion through the martensite to austeni...

background: due to underlying autoimmune background of guillain-barré syndrome (gbs), the possible role of infectious agents cytomegalovirus  (cmv) and  epstein-barr virus (ebv) and also due to association  of anti-ganglioside antibodies with gbs, the present study aimed to investigate the  associations   between serum anti-ganglioside antibodies (aga) level,  type  of  infection  and electrodi...

introduction: imatinib, a tyrosine kinase inhibitor which resulted in much improvement in the treatment of chronic myelogenous leukemia (cml), may adversely affect thyroid gland function. to date, assessment of thyroid function during imatinib therapy has limited to retrospective studies. the aim of this study was to evaluate the effects of imatinib on thyroid function in a prospective manner. ...

background and objective: hyperalgesia is one of the marked clinical signs of patients with diabetes mellitus that affects their lifestyle. this study was conducted to assess the anti-nociceptive effect of chronic administration of curcumin in streptozotocin (stz)-diabetic rats using formalin, hot tail immersion, and paw pressure tests. materials and methods: this study was conducted on 40 male...

objective(s): juglone is isolated from many species of the juglandaceae family and used as an anti-viral, anti-bacterial, and anti-tumor therapeutic. here, we evaluated juglone-induced antitumor effect in ovarian cancer skov3 cells. materials and methods: mtt assay was performed to examine juglone anti-proliferative effect. cell cycle and apoptosis were studied using flow cytometry in juglone-tr...

Background and objectives: Sesame (Sesamum indicum L.) seeds have been a well-known oil crop in the world for many centuries. Lignans are functionally important compartments of sesame. Sesamin and sesamol are the main sesame lignans, which have recently shown various activities with health benefits, like anti-oxidative, anti-proliferative, anti-atherosclerotic, anti-in...