the purpose of this study was to describe the association between grain yield and its components. the experiment was conducted in a randomized complete block design with three replicatsions. results of analysis showed that similar trends were observed for genotypic and phenotypic correlations and in most cases, the value for genetic correlation was greater than phenotypic value. 100-seed weight...

genetic parameters were estimated in a base and closed population of iranian honeybee colonies. data were obtained on 500-700 iranian native population of honey­bee colonies (honeybee breeding project in central region of iran) subject to 9 successive generation of selection. these populations had been selected for honey production, swarming behavior, and defense behavior. heritability of honey...

Background: Genomic instability is one of primary causes for malignant cell transformation. In this study induced genomic instability expressed as micronuclei in breast cancer (BC) patients with different stages of the disease compared with their unaffected first degree relatives (FDR) and normal unrelated controls was investigated. Materials and Methods: The background and net micronucleus fre...

Cardiomyopathies constitute a heterogeneous group of diseases with varying etiologies and clinical presentation. Advances in genetic testing have made it possible to establish genotype-phenotype relationships, determine prognosis, choose specific treatments the pediatric population. Therefore, objective this review is assist reasoning underscore importance etiological diagnosis different diseas...

Pulmonary hypertension is a convergent phenotype that presents late in the natural history of condition. The current clinical classification patients lacks granularity, and this impacts on development deployment treatment. Deep molecular phenotyping using platform ‘omic’ technologies beginning to reveal genetic architecture underlies phenotype, promising better targeting with new treatments. fu...

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The possibility to reprogram somatic human cells will greatly and deeply change genetic approach and allow the development of new tools to study genetics diseases. Indeed, our ability to study human genetic diseases suffers from the lack of valid in vitro models. The latter should (i) be originating from human primary cells, (ii) be able to self-renew for a long time and (iii) be able to differ...

connective tissue consists of cells separated by the extracellular matrix, whose composition and amount vary according to age, to functional requirements, and to the presence of pathologic conditions. within this non-random macromolecular assembly, collagens, elastin, proteoglycans and structural glycoproteins are mutually interdependent and modifications of one component, by extrinsic (environ...