The salts of trialkoxybenzoic acids and 2-amino alcohols showed a columnar liquid crystalline phase; in the case of the salt of a polymerizable acid and norephedrine, the photopolymerization proceeded efficiently in the liquid crystalline state, and the resultant solid adsorbed 2-amino alcohols size, regio-, and enantio-selectively.

The widespread use of powerful, low-frequency air gun pulses for seismic seabed exploration has raised concern about their potential negative effects on marine wildlife. An array of air guns creates a downward-directed, low-frequency pulse with most energy concentrated around 50 Hz and a back-calculated, broadband source level between 230 and 260 dB re 1 pPa (0 peak) with ocean-traversing poten...

Primary progressive aphasia (PPA) is a neurodegenerative clinical syndrome characterized primarily by progressive language impairment. Recently, consensus diagnostic criteria were published for the diagnosis and classification of variants of PPA. The currently recognized variants are nonfluent/agrammatic (PPA-G), logopenic (PPA-L) and semantic (PPA-S). OBJECTIVE To analyze the demographic dat...

Division of Molecular Pharmaceutics, School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC USA (SBY, AB, YG, DRT) Laboratory for Pharmacotechnology and Biopharmacy, Katholieke Universiteit Leuven, O&N2, Herestraat 49-Box 921, 3000 Leuven, Belgium (PPA; PA) Department of Pediatrics, Duke Clinical Research Institute, Duke University, Durham, NC, USA (DKB) DMD Fast F...

Fertility analysis is important in understanding past, current and future trends of population size, Composition and growth. Information on fertility levels, patterns and trends experienced by a country is important for socio-economic planning, monitoring and evaluating programs. In recent years the study of birth intervals has acquired importance because of its relationships to fertility. The ...

The recommendations that follow have been updated from the proposals of a Technical Subcommittee set up by the International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification (Jenkinson DH, Barnard EA, Hoyer D, Humphrey PPA, Leff P, and Shankley NP (1995) International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. IX. Recommenda...

A simple pyrene based probe (A3) derived from pyrene-1-carboxaldehyde and 2-amino-1-phenylpropan-1-ol shows unique optical response triggered by the concentration of lysine (Lys). This allows selective nanomolar detection of Lys via a cascade of processes, dynamic to static-excimer conversion in a ratiometric manner followed by aggregation-induced emission (AIE). Imaging of Lys in the human bre...

Since the addition of either ruminal fluid or a combination of phenylacetic and phenylpropionic acids (PAA/PPA) has previously been shown to dramatically improve cellulose degradation and growth of Ruminococcus albus, it was of interest to determine the effects of these additives on xylan-grown cultures. Although cell-bound xylanase activity increased when either PAA/PPA or ruminal fluid was ad...

Current diagnostic criteria classify primary progressive aphasia into three variants-semantic (sv), nonfluent (nfv) and logopenic (lv) PPA-though the adequacy of this scheme is debated. This study took a data-driven approach, applying k-means clustering to data from 43 PPA patients. The algorithm grouped patients based on similarities in language, semantic and non-linguistic cognitive scores. T...

Tinofedrine, a new derivative of l-norephedrine, was examined for cerebral vasodilator activity in man. Ten patients with reduced cerebral blood flow (CBF) and multi-infarct dementia were given the drug intravenously. Cerebral blood flow increased significantly by 28% from a mean of 43.3 to 55.5 ml/100 g/min.