BACKGROUND Although research in this area remains sparse, raising a child with some genetic disorders has been shown to adversely impact maternal health and family quality of life. The aim of this study was to investigate such impacts in families with a child with the CDKL5 disorder, a newly recognised genetic disorder causing severe neurodevelopmental impairments and refractory epilepsy. MET...

BACKGROUND Health-related quality of life may affect morbidity and survival in end-stage renal disease, but it is not clear whether coexisting comorbidity and other known prognostic variables could account for such an association. METHODS To study the relationship between health-related quality of life and morbidity and survival, we carried out an inception cohort study in patients starting c...

OBJECTIVE US general population norms for mail administration of the Medical Outcomes Study 36-Item Short Form Version 2 (SF-36v2) were established in 1998. This article reports SF-36v2 telephone-administered norms collected in 2005-2006 for adults aged 35-89 years. STUDY DESIGN AND SETTING The SF-36v2 was administered to 3,844 adults in the National Health Measurement Study (NHMS), a random-...

Heart failure is a chronic debilitating disease that affects all aspects of a person's life, including physical, mental and spiritual dimensions. The associations among these dimensions, and the relationship to overall health status, have not been clearly identified. The purpose of this quantitative, descriptive study was to explore differences between spirituality, depressive symptoms, and qua...

PURPOSE The purpose of this article was to systematically review the literature to identify the impact of primary Sjögren's syndrome (pSS) on specific health-related quality of life (HRQoL) domains. METHODS A meta-analysis was performed, and the related articles were searched in Medline, Embase, Cochrane Library, China National Knowledge Infrastructure, China Biology Medicine, and Web of Scie...

OBJECTIVE To examine the relationship between two measures that can be used to examine quality life among pediatric burn survivors. DESIGN Prospective, correlational study. SETTING Acute and rehabilitation pediatric burn care facility. PARTICIPANTS Eighty young adult survivors of pediatric burns, who were 18-28 years of age, with burns of 30% or greater, and were at least 2 years after bu...

BACKGROUND The Lysholm knee scale, first published in 1982, is an eight-item questionnaire designed to evaluate patients after knee ligament injury. However, as a tool developed in English, its use as a validated instrument has been limited to English-language populations. QUESTIONS/PURPOSES The objectives of this study were to test the ease of use, reliability, and validity of a Turkish-lang...

BACKGROUND The purpose of this study was to identify the incidence of frailty and to investigate the relationship between frailty status and health-related quality of life (HRQoL) in the community-dwelling elderly population who utilize preventive health services. METHODS People aged 65 years and older who visited a medical center in Taipei City from March to August in 2011 for an annual rout...

BACKGROUND Low back pain is a commonest musculoskeletal disorder affecting majority of people. Activity limitations are difficulties an individual may have in executing activities resulting from person's functioning and disability. According to the fear-avoidance model of low back pain, individuals who perceive pain as a sign of potential damage are more likely to avoid behaviors that increase ...

PURPOSE A number of previous studies have shown inconsistencies between sub-scale scores and component summary scores using traditional scoring methods of the SF-36 version 1. This study addresses the issue in Version 2 and asks if the previous problems of disagreement between the eight SF-36 Version 1 sub-scale scores and the Physical and Mental Component Summary persist in version 2. A second...