A simplified dynamic model generates patient-specific estimates of intracranial pressure and suggests a path forward for bringing simulated (SIM) physiologic models to the patient's bedside.

ceeds supply.@ Adenosine measurement is difficult in any given circumstance, as elements such as endothe hal cell and blood uptake and release, interstitial concentration, intracellular binding with SAH-hydro lase, and flow all influence venous adenosine concen trations. Adenosine is removed from tissues either by phos phorylation to AMP by adenosine kinase or by deam ination by adenosine deami...

Root resorption is a physiologic event for the primary teeth. It is still unclear whether odontoclasts, the cells which resorb the dental hard tissue, are different from the osteoclasts, the cells that resorb bone. Root resorption seems to be initiated and regulated by the stellate reticulum and the dental follicle of the underlying permanent tooth via the secretion of stimulatory molecules, i....

Sleep is a time of varying physiologic and metabolic activity (2, 3). Many of the metabolic patterns which occur during sleep have not been well characterized. One area which falls into this category concerns the changes in blood glucose that occur during sleep. Previous studies on normal subjects have given conflicting results. Hyperglycemia, normoglycemia, and hypoglycemia have been reported ...