Historically, amyloids were perceived as toxic/irreversible protein aggregates associated with neurodegenerative disorders including Alzheimer's and Parkinson's diseases. Recent papers are challenging this perception by uncovering widespread cellular roles for physiological amyloidogenesis. These findings suggest that the amyloid-fold should be considered, alongside the native-fold and unfolded...

The high comorbidity between psychiatric disorders and cardiovascular disease has received increasing attention, yet little is known about the processes linking the two. One plausible contributing mechanism is the tendency of those with psychiatric disorders to ruminate on stressful events. This phenomenon, sometimes called perseverative cognition, can extend the psychological and physiological...

Nutrition regulates energy balance; however, dysfunction of energy balance can cause metabolic disorders, such as obesity and diabetes. Fatty acids are an essential energy source and signaling molecules that regulate various cellular processes and physiological functions. Recently, several orphan G protein-coupled receptors were identified as free fatty acid receptors (FFARs). GPR40/FFAR1 and G...

Recently, metabolomics has grown rapidly in the fields of food and agriculture. Complex physiological changes after harvest prompted development a new metabolomic analytical method offering more profound insight into these changes. This review presents feasibility approach to elucidate during ripening, senescence, disorders. Additionally, we introduce for authentication agricultural products. C...

introduction: vulnerability has an important role in ptsd, which can be either genetic or acquisitive. according to research, the disorder coexists simultaneously with at least another psychiatric disorder and can be a disorder comorbid with a predictive factor, which influences the process from afflicting to medication. this study was performed to determine ptsd accompanying disorders in the p...

Psychosomatic disorders are defined as disorders characterized by physiological changes that originate partially from emotional factors. This article aims to discuss the psychosomatic disorders of the oral cavity with a revised working type classification. The author has added one more subset to the existing classification, i.e., disorders caused by altered perception of dentofacial form and fu...

Food anticipatory hormonal responses (cephalic responses) are proactive physiological processes, that allow animals to prepare for food ingestion by modulating their levels in response cues. This process is important digesting food, metabolizing nutrients and maintaining glucose within homeostasis. In this systematic review, we summarize the evidence from animal human research on cephalic respo...