9 The Rockefeller University Press $30.00 J. Cell Biol. Vol. 215 No. 1 9–11 www.jcb.org/cgi/doi/10.1083/jcb.201609084 A protein’s location reflects its function. This is especially apparent in neurons because of their complex morphologies and highly specialized membrane domains. For example, the most basic division in neuronal morphology is the distinction between dendrites and axons. A neuron ...

OBJECTIVE To evaluate the effect of a bridge safety fence in preventing suicide. METHODS We examined suicides from jumping off the Memorial Bridge in Augusta, Maine, from 1 April 1960 to 31 July 2005. The safety fence was installed during 1983, the mid-point of the study period. RESULTS 14 suicides from the bridge were identified; all occurred before installation of the safety fence. The nu...

The thermodynamic constants of oxygen binding to cobalt “picket fence” porphyrin complexes, meso-tetra(a,o,a,oo-pivalamidophenyl)porphyrinatocobalt(II)1 -methylimidazole and 1,2-dimethylimidazole, are reported. In contrast to previously studied cobalt porphyrins, these complexes bind oxygen with the same affinity as cobalt substituted myoglobin and hemoglobin. Solvation effects are discussed as...

Purpose Linear accelerator quality assurance (QA) in radiation therapy is a time consuming but fundamental part of ensuring the performance characteristics delivering machines. The goal this work to develop an automated and standardized QA plan generation analysis system Oncology Information System (OIS) streamline process. Methods Automating process includes two software components: AutoQA Bui...

The effects of a porous fence with a nonuniform porosity on flow fields are investigated numerically. First, an experiment with a non-uniform porous fence located in a wind tunnel is performed to obtain a reference data set. Then, a numerical model that utilizes the finite volume schemewith a weakly compressible-flowmethod to solve the continuity and momentum equations is developed. The numeric...

In this paper, a numerical study on pressure characteristics of fluid passing through a configuration of sudden expansion with central restriction only and sudden expansion with central restriction and fence has been carried out. The two dimensional steady differential equations for conservation of mass and momentum are solved for Reynolds number ranging from 50 to 200, percentage of central re...

The presence of large-scale vortices with high spanwise coherence has been observed in the atmospheric boundary layer (ABL). This study investigates an innovative technique to generate a large-scale spanwise vortex from the oscillation of a surface-mounted fence in a wind tunnel. Characteristics of the large vortex with a well-defined length scale and its development with downstream distance be...