Cucurbita maxima (CM) seed oil is commonly used in Indian folk medicine to treat various ailments. We have investigated the effect of CM seed oil on memory impairment induced by scopolamine in rats. Male adult Wistar rats were administered scopolamine 1 mg/kg body weight, i.p. or 1.25 mg/kg body weight, s.c. to induce memory impairment. The nootropic agent piracetam 100 mg/kg body weight, i.p. ...

Frontotemporal dementia (FTD) is one of three neurobehavioural syndromes produced by frontotemporal lobar degeneration. Despite the importance of FTD as a cause of dementia, especially in younger age groups, and a rationale for therapies targeting serotonergic and dopaminergic systems, there have been no large scale treatment trials in FTD. Moreover, there is no consensus on standards to facili...

Introduction Long-term benzodiazepine use is common although not routinely recommended. While their dependence potential notorious, cognitive problems due to chronic have only recently been intensively studied. Residual symptoms may linger months after successful discontinuation and significantly limit optimal functional outcome in abstinent individuals. Objectives We present a series of cases,...

Introduction: In this study, the patients diagnosed with breath holding spell (BHS) or anoxic epileptic seizures and initiated at least one out of iron piracetam levetiracetam therapies were evaluated. Material Methods: We retrospectively evaluated 194 BHS patients. Iron therapy was in case deficiency anemia ferritin values under 12 ng/dl even if there no anemia. The having anemia, low administ...

Specific stability indicating reverse-phase liquid chromatography (RP-LC) assay method (SIAM) was developed for the determination of cinnarizine (Cinn)/piracetam (Pira) and cinnarizine (Cinn)/heptaminol acefyllinate (Hept) in the presence of the reported degradation products of Cinn. A C18 column and gradient mobile phase was applied for good resolution of all peaks. The detection was achieved ...