Interest in understanding the underlying mechanisms of the placebo effect has considerably grown during the last few decades. Studies made in this sense have led to a change in the conception of this peculiar phenomenon, and nowadays the placebo effect is viewed as a psychobiological event resulting from the interaction between individual patient factors and factors relating to the physician an...

Effect of Bamlanivimab vs Placebo on Incidence COVID-19 at Skilled Nursing and Assisted Living Facilities

518 ABSTRACT The placebo effect has been a source of fascination, irritation, and confusion within biomedicine over the past 60 years.Although scientific investigation has accelerated in the past decade, with particular attention to neurobiological mechanisms, there has been a dearth of attention to developing a general theory of the placebo effect. In this article, we attempt to address this g...

Results All participants recognised the term ‘placebo’ and exhibited diverse opinions as to how the placebo effect works and whether the placebo effect even exists. Honest doctorpatient communication was highly valued by participants, who typically saw placebo prescriptions as deceitful and therefore wrong. However, they also expressed the belief that that deception is necessary for the patient...

purpose: to evaluate the effect of oral tranexamic acid, oral prednisolone and placebo on prevention of recurrent hemorrhage in traumatic hyphema. methods: this randomized placebo-controlled double-blind clinical trial was performed on 182 subjects affected by hyphema after blunt trauma. the patients were hospitalized for at least 5 days and were randomly assigned for receiving oral tranexamic ...

Much literature has been written in the field of child psychiatry regarding the placebo as a tool to test drug efficacy in clinical trials, but quite little regarding the placebo effect itself or its clinical use in child psychiatry. In this article, we aim to critically review the literature regarding the placebo effect in children and adolescents with mental disorders, focusing especially on ...

Although placebo pills are supposed to have no pharmacological activity, people taking placebo pills describe a variety of positive (i.e., placebo phenomenon) and negative (i.e., nocebo phenomenon) reactions. This has major clinical implications. Placebo reactions account for a substantial part of improvement when treating patients with hypertension, mental disorders, and even after surgical pr...

Tacrine is a cholinesterase inhibitor with activity in the central nervous system originally marketed for the reversal of competitive neuromuscular blockade. Because a marked reduction in cholinergic neurons is a hallmark of brain changes in Alzheimer disease, tacrine has been studied in two placebo-controlled clinical trials of patients with probable Alzheimer disease. Standard analysis of var...

OBJECTIVES To study the analgesic effect of acupuncture and placebo acupuncture and to explore whether the type of the placebo acupuncture is associated with the estimated effect of acupuncture. DESIGN Systematic review and meta-analysis of three armed randomised clinical trials. DATA SOURCES Cochrane Library, Medline, Embase, Biological Abstracts, and PsycLIT. Data extraction and analysis ...