purpose: to compare rose-k and conventional rgp contact lenses in terms of visual acuity, visual function and comfort in keratoconus patients. method: fifty-four patients with keratoconus were randomly fitted with rose-k and conventional rgp contact lens (wohlk contact lens), by one experienced ophthalmologist using a standard (three touch point) approach. general and demographic information, k...

purpose: to determine the effect of using rigid gas permeable (rgp) contact lenses in improvement of involuntary eye movements and visual functions in hyperopic astigmatism patients with congenital nystagmus. methods: this prospective interventional case series study was conducted on patients with congenital nystagmus and hyperopia equal or more than +0.5 d and astigmatism more than -1 d, who w...

  Background: Increased oxygen free radical and reduced glutathione level in the eye lens are important risk factor for cataract formation. The antioxidative property and increasing cellular and extra cellular glutathione level have been reported by several herbal medicines including silymarin.  Objective: In present interventional study Silybum marianum L. seed extract (silymarin) was tested a...

Introduction: Critical organs and structures may receive significant amounts of irradiation even if they are not the target of radiotherapy or located outside the treatment field. Although the sensitive thyroid gland and lens are not directly the targets of treatment, they can be affected by irradiation during the treatment of tumours in head and neck region. The purpose of thi...

Introduction: Among the components of the extracellular matrix (ECM) and basement membrane (BM), laminitis heterotrimeric glycoprotein (laminin) and collagen type IV are the most important. In a previous study we have examined the role of collagen type IV in the developing lens capsule. The present study aims to determine the appearance and distribution of laminin in the BM and ECM of lenses ...

  Introduction: The study of the cause of death during the last few decades has shown that death due to infectious diseases has been declining and has been rising due to noninvasive diseases, especially cancers and accidents. Cancer is considered as one of the fatal diseases, and every year, more than 10.9 million people worldwide are diagnosed with the disease. Mater...

Introduction: Consumption of morphine, during pregnancy, in addition to inducing defects in the mother’s nervous system function, caused defects or delays in the formation and evolution of embryonic visual system. In the present study, changes in lens development were assessed in embryos exposed to morphine in utero. Methods: Female Wistar rats (250-300 g) were mated with male rats and pregnanc...

Background: It has been estimated that 67 million people worldwide are affected with a primary glaucoma and that one-third have primary angle closure glaucoma. We aimed to determine the biometric differences between the eyes of patients with acute attack of primary angle closure and their non-involved fellow eyes. Methods: Twenty eight patients with acute attack of primary angle closure were re...

introduction: in cases of poor satisfaction with aphakic glasses and intolerant or reluctant to use contact lenses, secondary intraocular lens (iol) implantation provide an alternative aphakic vision correction. this study aimed to evaluate surgical problems.  intraoperative and postoperative complications and visual acuity outcomes of secondary anterior and posterior chamber intraocular lens i...

Different antibiotics have different characteristics but the aspect of antibiotic stability is the main concern of the pharmacist when dispensing the drug. The stability of drug such as chemical stability, physical stability, microbiological stability, therapeutic stability and toxicological stability will ensure its therapeutic effect. There are some factors that may affect antibiotics’ effect...