Two patients with end-stage-renal-disease on continuous ambulatory peritoneal dialysis (CAPD) presented with pleural effusions. The aspirated fluid was categorised as transudate, based on alkaline pH, low protein and lactic dehydrogenase level. A striking feature of the pleural fluid was, its very high glucose content that resulted from translocation of dextrose containing peritoneal dialysate ...

AIMS The aim of this study was to evaluate the physicochemical properties of the pleural mesothelial barrier and of the biological markers that facilitate or eliminate the passage of molecules through the pleura. METHODS AND MATERIAL Pleural fluid samples from sixty-five patients with heart failure were analyzed. The biological markers studied were lactate dehydrogenase (LDH), adenosine deami...

Sixty patients of pleural effusion with different aetiology are described. Various microbiological and biochemical parameters were done simultaneously in blood and pleural fluid to differentiate tuberculosis and non-tuberculosis effusions. Some biochemical tests were thought to be helpful in differential diagnosis but no single parameter was found diagnostic. Routine investigations of pleural f...

Courtice and Simmonds (1) have shown the importance of lymphatic drainage from the serous cavities. They showed that protein labeled with T-1824 and injected into the pleural cavity in cats is removed exclusively by the lymphatic vessels. The rate of removal of labeled protein from the pleural cavity therefore is a measure of lymphatic flow. Burgen and Stewart (2) described a method for measuri...

We report the penetration of liposomal amphotericin B into the pleural fluid of a patient with pulmonary zygomycosis and empyema. The ratio of area under the concentration-versus-time curve in pleural fluid (AUC(pleural fluid)) to that in serum (AUC(serum)) for liposomal amphotericin B over 24 h was 9.4%, with pleural fluid concentrations of 2.12 to 4.91 microg/ml. Given the relatively low leve...

STUDY OBJECTIVES To determine if the diagnosis of pleural malignancy is dependent on the volume of pleural fluid sampled. DESIGN AND SETTING Single-center retrospective chart review. PATIENTS Two hundred eighty-two patients who underwent diagnostic thoracentesis between October 1, 1998, and June 30, 1999. INTERVENTIONS Charts were analyzed for volume of fluid, pathologic and clinical diag...

We read with interest the recent paper by QUEROL JM, BARBE F, MANRESA F, EsTEBAN L and CANETE [1]. The authors presented some patients with tuberculous pleural effusion and adenosine deaminase activity (ADA) values less than 43 U·I-• We reported previously that ADA values (Guisti method) were statistically significantly higher in tuberculous pleural effusions than in most other diseases [2]. Hi...

Tuberculosis (TB) is one of the most common infectious diseases in developing countries including Nepal. Delay in diagnosis and treatment of tuberculosis results in poor prognosis of the disease. This study was conducted to estimate diagnostic cut off values of Adenosine Deaminase (ADA) in cerebrospinal fluid (CSF) and pleural fluid and to evaluate the sensitivity, specificity, positive and neg...

Controversy exists regarding the clinical utility of pleural fluid pH, lactate dehydrogenase (LDH), and glucose for identifying complicated parapneumonic effusions that require drainage. In this report, we performed a meta-analysis of pertinent studies, using receiver operating characteristic (ROC) techniques, to assess the diagnostic accuracy of these tests, to determine appropriate decision t...

Chylous pleural effusion is characterized by milky-appearing fluid with elevated triglyceride content and presence of chylomicrons in the pleural space. Even though patients with lymphoma sometimes present with malignant pleural effusion, chylous effusion is rarely encountered as a presenting feature in such patients. We present a 47-year-old woman diagnosed as follicular lymphoma who presented...