introduction: ischaemic-reperfusion nerve injury has been suggested as the mechanism for post-tourniquet limb paralysis. as dexamethasone (dex) has been shown to prevent ischaemic-reperfusion process in some tissues, we tested the hypothesis that this drug would reduce tourniquet induced nerve injury. methods: 36 male wistar rats (200-250 gr) were chosen and divided randomly into 6 equal groups...

The use of lidocaine in concentrations less than 5% for spinal anesthesia may be advantageous but has not been carefully studied. Lidocaine 50 mg (1.5% with dextrose and 1.5% dextrose-free) was administered to eight volunteers in a randomized, double blind, cross-over fashion. All of these subjects had previously received 5% lidocaine with dextrose using the same experimental protocol. Sensory ...

BACKGROUND To assess the hemostatic effect of QuikClot Combat Gauze (QCG) compared to that of standard gauze during cruciate-retaining total knee arthroplasty (TKA). METHODS Sixty knees underwent TKA using a pneumatic tourniquet in this prospective randomized study. After implantation of the femoral and tibial components and hardening of the bone cement, the tourniquet was deflated and QCG (g...

Background & Objective: Induction of general anesthesia has been known to raise the intraocular pressure (IOP). The effect is more pronounced at time intubation. Similarly, applying pneumatic tourniquets associated with rise in IOP. We compared effects and combined spinal-epidural (CSEA) on IOP lower extremity surgeries employing tourniquets.
 Methodology: A total 50 patients, aged ove...

Longitudinal and radial tissue-fluid pressure distributions were determined beneath and adjacent to wide (12 and 18 cm) pneumatic tourniquet cuffs placed on intact human cadaveric arms and legs, respectively. Tissue fluid pressures exhibited relatively broad maxima at midcuff, and in most cases showed no differences at the various depths studied. Limb circumference was not a determining factor ...

BACKGROUND Acute ischemia reperfusion injury (IRI) results in muscle atrophy and functional loss. Although studies have shown that stem cells can improve muscle function in chronic ischemia caused by vascular diseases, none investigated whether stem cells can improve muscle function following acute IRI. The primary purpose of this study was to determine whether transplantation of muscle progeni...

Recently, the rehabilitation devices using a soft pneumatic actuator for disabled are actively researched and developed because of the insufficient number of PT. In the previous study, the wrist rehabilitation device using flexible robot arm that consisted of three flexible pneumatic cylinders was proposed and tested. In this study, the wearable wrist rehabilitation device is proposed and teste...

A small pneumatic cuff inflated around the knee was used to produce tourniquet paralysis in baboons. A cuff pressure of 1,000 mm Hg maintained for one to three hours produced paralysis of distal muscles lasting up to three months. Nerve conduction studies showed that most of the motor fibres to the abductor hallucis muscle were blocked at the level of the cuff and that they conducted impulses n...

We developed a technique for measuring patient limb occlusion pressure (LOP) through a tourniquet cuff that overcomes many limitations of existing LOP measurement techniques. The purpose of the study is to determine whether the LOP measured by the proposed technique is statistically or clinically different from that measured by the gold standard Doppler ultrasound technique. The study used rand...