نتایج جستجو برای: pneumococcal

تعداد نتایج: 11690  

Journal: :Clinical and vaccine immunology : CVI 2015
Lance E Keller Xiao Luo Justin A Thornton Keun-Seok Seo Bo Youn Moon D Ashley Robinson Larry S McDaniel

Current vaccinations are effective against encapsulated strains of Streptococcus pneumoniae, but they do not protect against nonencapsulated Streptococcus pneumoniae (NESp), which is increasing in colonization and incidence of pneumococcal disease. Vaccination with pneumococcal proteins has been assessed for its ability to protect against pneumococcal disease, but several of these proteins are ...

Journal: :Allergologia et immunopathologia 2016
A Quezada L Maggi X Norambuena J Inostroza F Quevedo

BACKGROUND To analyse specific immune response to the 23-valent pneumococcal polysaccharide vaccine by measuring pneumococcal antibodies in children with asthma and with respiratory recurrent infection (RRI) as compared to healthy children. METHODS The study included 60 children, divided into three groups: 20 with asthma, 20 with RRI, and 20 healthy controls. Post-vaccination specific IgG ant...

2017
Angela B. Brueggemann Caroline L. Harrold Reza Rezaei Javan Andries J. van Tonder Angus J. McDonnell Ben A. Edwards

Bacteriophages (phages) infect many bacterial species, but little is known about the diversity of phages among the pneumococcus, a leading global pathogen. The objectives of this study were to determine the prevalence, diversity and molecular epidemiology of prophages (phage DNA integrated within the bacterial genome) among pneumococci isolated over the past 90 years. Nearly 500 pneumococcal ge...

2014
Iris De Schutter Anne Vergison David Tuerlinckx Marc Raes Julie Smet Pierre R. Smeesters Jan Verhaegen Françoise Mascart Filip Surmont Anne Malfroot

Community-acquired pneumonia (CAP) is a major cause of morbidity in children. This study estimated the proportion of children with pneumococcal CAP among children hospitalised with CAP in Belgium and describes the causative serotype distribution after implementation of the 7-valent pneumococcal conjugate vaccine. Children 0-14 years hospitalised with X-ray-confirmed CAP were prospectively enrol...

2012
Catherine Weil-Olivier Mark van der Linden Iris de Schutter Ron Dagan Lorenzo Mantovani

BACKGROUND The burden of invasive pneumococcal disease in young children decreased dramatically following introduction of the 7-valent pneumococcal conjugate vaccine (PCV7). The epidemiology of S. pneumoniae now reflects infections caused by serotypes not included in PCV7. Recently introduced higher valency pneumococcal vaccines target the residual burden of invasive and non-invasive infections...

2015
Nicola Principi Susanna Esposito

Several epidemiological studies have evidenced that children with underlying chronic conditions are at increased risk of pneumococcal infections with higher case-fatality rates than healthy subjects. Because pharyngeal pneumococcal carriage is a prerequisite for pneumococcal infection development, the high colonization rates found in these subjects is the most important reason for this phenomen...

2017
Myint Tin Tin Htar Anke L. Stuurman Germano Ferreira Cristiano Alicino Kaatje Bollaerts Chiara Paganino Ralf René Reinert Heinz-Josef Schmitt Cecilia Trucchi Thomas Vestraeten Filippo Ansaldi

INTRODUCTION S. pneumoniae can cause a wide spectrum of diseases, including invasive pneumococcal disease and pneumonia. Two types of pneumococcal vaccines are indicated for use in adults: 23-valent pneumococcal polysaccharide vaccines (PPV23) and a 13-valent pneumococcal conjugate vaccine (PCV13). OBJECTIVE To systematically review the literature assessing pneumococcal vaccine effectiveness ...

1999
A N Siriwardena

The Department of Health recommends pneumococcal vaccination opportunistically or when immunising against influenza. This was a study in one general practice to assess the feasibility of targeting patients for pneumococcal vaccination in primary care. We also examined the rate of uptake of pneumococcal vaccine in identified risk groups after one year of a pneumococcal vaccination programme. A s...

Journal: :The New England journal of medicine 2015
Marc J M Bonten Susanne M Huijts Marieke Bolkenbaas Chris Webber Scott Patterson Samantha Gault Cornelis H van Werkhoven Anna M M van Deursen Elisabeth A M Sanders Theo J M Verheij Michael Patton Anne McDonough Anita Moradoghli-Haftvani Helen Smith Tracey Mellelieu Michael W Pride Graham Crowther Beate Schmoele-Thoma Daniel A Scott Kathrin U Jansen Rita Lobatto Bas Oosterman Nils Visser Esther Caspers Andre Smorenburg Emilio A Emini William C Gruber Diederick E Grobbee

BACKGROUND Pneumococcal polysaccharide conjugate vaccines prevent pneumococcal disease in infants, but their efficacy against pneumococcal community-acquired pneumonia in adults 65 years of age or older is unknown. METHODS In a randomized, double-blind, placebo-controlled trial involving 84,496 adults 65 years of age or older, we evaluated the efficacy of 13-valent polysaccharide conjugate va...

Journal: :The New England journal of medicine 2005
Thomas R Talbot Tina V Hartert Ed Mitchel Natasha B Halasa Patrick G Arbogast Katherine A Poehling William Schaffner Allen S Craig Marie R Griffin

BACKGROUND The risk of invasive pneumococcal disease among persons with asthma is unknown. METHODS We conducted a nested case-control study to examine the association between asthma and invasive pneumococcal disease. The study population included persons 2 to 49 years of age who were enrolled in Tennessee's Medicaid program (TennCare) for more than one year during the study period (1995 throu...

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