epidermal growth factor (egf) is a polypeptide molecule, with important functions in epithelial growth and wound repair. it exerts its effects on cells by binding to receptors on the cell surface. the aim of this study was to evaluate and compare salivary egf levels in patients with gingivitis and advanced periodontitis as well as in healthy controls.unstimulated salivary samples were collected...

Background Hyaluronan is a critical component of the extracellular matrix and contributes significantly to tissue hydrodynamics and cell migration and proliferation. Studies have demonstrated its anti-inflammatory, antibacterial, and regenerative effects. The present study aimed to assess the clinical effects of the subgingival application of 0.8% hyaluronic acid gel as an adjunct to scaling an...

Background. Recent reports have found a positive relationship between periodontitis and the hormones cortisol and dehydroepiandrosterone (DHEA). We investigated the associations between those levels and periodontitis in never-smokers and smokers of elderly subjects. Subjects and Methods. Cortisol and DHEA levels in saliva were determined in 171 subjects (85 males, 86 females), with clinical exa...

AIMS AND OBJECTIVES Obtaining root coverage has become an important part of periodontal therapy. The aims of this studyare to evaluate the clinical efficacy of acellular dermal matrix graft in the coverage of denuded roots and also to examine the change in the width of keratinized gingiva. MATERIALS AND METHODS A total of 20 sites with more than or equal to 2 mm of recession depth were taken ...

This clinical study evaluated the influence of scaling and root planning (SRP), with and without the use of tetracycline-loaded bovine absorbent membrane, in the reduction of periodontal pockets according to 3 parameters: probing pocket depth (PPD), bleeding on probing (BOP) and plaque index (PI). Twenty-four patients were selected totalizing 144 random teeth divided in 2 groups (n=72 teeth) - ...

BACKGROUND The success of combined periodontal and orthodontic approach in the treatment of aggressive periodontitis patients with the pathologic extruded anterior teeth is a main concern and stability of the treatment results is an important factor to evaluate the treatment. The present study investigated the periodontal parameters at the end of the orthodontic treatment in patients with the a...

Materials and Methods: 28 CP and 17 GAgP patients were included in the study and their cigarette consumption was determined by verbal questioning. In each patient, 4 sites with pocket depths of 5mm or greater were selected. At each site the modified gingival index (MGI), plaque index (PlI), bleeding on probing (PD), suppuration (Supp), probing depth (PD) and relative attachment level (RAL) were...

Periodontal disease is considered a risk factor in dental implant treatment. The purpose of this study was to investigate the periodontal conditions in patients requesting dental implant therapy. A total of 169 patients visiting Department of Oral and Maxillo-Facial Implantology at Tokyo Dental College Chiba Hospital were targeted. The following intraoral parameters were measured in each patien...